SynthesisBMC pediatrics2025
Incidence of neonatal asphyxia and associated risk factors: a systematic review and cumulative meta-analysis.
Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo analyze the incidence of neonatal asphyxia and its associated related risk factors and provide reference for reducing the incidence and mortality of neonatal asphyxia.
methodsPubMed, Web of Science, CNKI, and Wanfang were searched for cross-sectional/case-control studies (inception-December 31, 2024). After dual-independent screening (PROSPERO: CRD420251118897), 18 studies (n = 737,839 neonates) were included. Quality was assessed using AHRQ. Random/fixed-effects models were applied based on I² thresholds. Temporal trends were explored via sequential meta-analysis by publication year. Sensitivity and publication bias analyses were conducted.
resultsA total of 18 studies was included, involving 737,839 neonates, and the overall quality of the literature was acceptable. The combined incidence of neonatal asphyxia and its 95% CI was 7% (5%, 8%). Factors associated with neonatal asphyxia included instrumental delivery, primiparity, preterm birth, and low birth weight. The pooled ORs and 95% CIs for meta-analyzed risk factors of neonatal asphyxia (instrument-assisted delivery, primiparity, preterm birth, and low birth weight) were 3.10 (1.79, 5.38), 3.51 (2.15, 5.74), 2.18 (1.54, 3.09), and 2.85 (2.33, 3.49), respectively. According to the order of publication, cumulative Meta-analysis showed that the OR values and 95% CI of instrumental delivery, primiparity, preterm birth, and low birth evolved had a trend over time.
conclusionThe incidence of neonatal asphyxia remains an important public health concern. Findings suggest that neonates born following instrumental delivery, or with primiparity, preterm birth, or low birth weight could be considered for more careful monitoring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.