ArticleBMC veterinary research2025
Mycobacterium avium-complex infection mimicking lymphoma in a miniature schnauzer.
Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- First identification of orf virus from an outbreak of contagious ecthyma in Polish sheep.Journal of veterinary research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis case report describes an uncommon Mycobacterium avium infection mimicking lymphoma in a dog. CASE PRESENTATION: A 1.5-year-old female Miniature Schnauzer presented with persistent lymphadenopathy, fever, and diarrhea, which were refractory to conventional therapy. Hematological and biochemical analyses revealed anemia, thrombocytopenia, elevated liver enzymes, creatine kinase, glutamate dehydrogenase, lactate dehydrogenase, hyperkalemia, low IgG levels, and euthyroid sick syndrome. Ultrasonography confirmed generalized visceral, retroperitoneal, and peripheral lymphadenopathy with concurrent inflammatory reactions, splenomegaly, and hepatomegaly characterized by heterogeneous parenchyma and multiple foci, further supporting the suspicion of lymphoma. However, cytological examination of an enlarged lymph node showed no evidence of lymphoma but revealed the presence of numerous bacilli suggestive of mycobacterial infection. Histopathological evaluation of a surgically excised lymph node similarly failed to confirm lymphoma. Mycobacterium avium was successfully cultured from the lymph node tissue and identified via the GenoType Mycobacterium CM test. Based on antimicrobial susceptibility testing, the initial therapeutic regimen of enrofloxacin, azithromycin, and rifampicin was modified to clarithromycin. Adjunctive treatments included blood transfusion, levothyroxine, prednisolone, omeprazole, sucralfate, parapoxvirus ovis, and soy phospholipids. Despite a temporary clinical improvement, the patient's condition progressively worsened, and the dog succumbed to the disease after three months.
conclusionsThis case underscores the importance of including Mycobacterium avium in the differential diagnosis of generalized lymphadenopathy, particularly in Miniature Schnauzers. The findings support the routine use of Ziehl-Neelsen staining during cytological examinations to prevent misdiagnosis, especially in breeds predisposed to atypical infections. It also emphasizes the crucial role of targeted antimicrobial therapy in managing such cases, although the prognosis remains guarded.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.