Evidence map›Paper›PMID 41121078›Full record

ArticleCancer cell international2025

PMA exerts anti-leukemia effect in Ph

Xu Wang, Jinfeng Tan, Jie Tang, Teng Wang, Dachuan Zeng, Renren Zheng, Jing Hu, Suotian Liu, Wei Wei, Jie Zou and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer cell international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xu Wang *Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jinfeng Tan *Department of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Jie Tang *Department of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Teng WangDepartment of Hematology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Dachuan ZengDepartment of Clinical Laboratory, Women and Children's Hospital of Chongqing Medical University, Chongqing, China.
Renren ZhengDepartment of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Jing HuDepartment of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Suotian LiuDepartment of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Wei WeiDepartment of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Jie ZouDepartment of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Yan DuDepartment of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Zhenglan HuangDepartment of Clinical Hematology, Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China. zhenglan@cqmu.edu.cn.
Miao GaoDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. waters@hospital.cqmu.edu.cn.

Funding

2023 Outstanding Young Teachers Program of Sanquan College of Xinxiang Medical University SQ2023YQJH08Program for Youth Innovation in Future Medicine, Chongqing Medical University W0012The Natural Science Foundation of Chongqing CSTB2022NSCQ-MSX0764
6 · The paper itself

Abstract

backgroundPhiladelphia chromosome-positive acute lymphoblastic leukemia (Ph

methodsWe investigated the biological effects of PMA on Ph

resultsWe found that PMA could promote apoptosis, inhibit proliferation and promote differentiation of human Ph

conclusionsPMA exerts an anti-leukemia effect in Ph

Indexed as

Acute lymphoblastic leukemiap-ERKPhiladelphia chromosomePKCPMA

Identifiers

PMID41121078
PMCPMC12542116

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.