ArticleBMC infectious diseases2025
Clinical features and sequelae of pediatric osteomyelitis following surgical treatment: a 10-year retrospective study.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Current Trends and Future Directions in the Diagnosis and Management of Pediatric Orthopedic Disorders.Cureus · 2026Review
- ["Chongqing experiences" in treatment of bone infections].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
aimOsteomyelitis (OM) in children is a severe infectious disease, and its sequelae are common. The purpose of this study was to analyze the clinical features and sequelae of pediatric patients following surgical treatment. PATIENTS AND
methodsWe reviewed all pediatric patients with OM at our clinical center who underwent surgical debridement and antimicrobial therapy from January 2013 to December 2023. Patients were followed for at least 1 year to evaluate clinical outcomes and the occurrence of sequelae. Risk factors associated with sequelae were analyzed via Logistic regression.
resultsA total of 220 pediatric patients with a mean age of 11.69 ± 3.79 years were included. Of these, 151 (68.6%) were male. The majority were due to hematogenous infection (56.8%), while a significant proportion of patients had chronic infections with 149 (67.7%) had more than three month infection duration. The most frequently involved bones were the tibia (44.5%) and femur (29.5%). In addition, 103 patients (46.8%) had a detected pathogen, with Staphylococcus aureus (34.1%) being the most common, followed by Pseudomonas aeruginosa (4.1%) and Staphylococcus epidermidis (3.2%). After a median follow-up of 2 years (range: 1-6 years), 8 patients (3.6%) had infection recurrence; However, they were completely cured after revision surgery. A total of 37 patients (16.8%) reported sequelae, including growth arrest (n = 21), joint injury (n = 16), limb deformities (n = 7), chronic pain (n = 3), and pathologic fractures (n = 2). Regression analysis showed that the use of an external fixator (OR = 8.85, p = 0.001), traumatic infection (OR = 9.88, p = 0.002), prolonged infection duration (≥ 3 months) (OR = 8.00, p = 0.007), and multiple debridements (n ≥ 2) (OR = 5.49, p = 0.021) were risk factors for sequelae, after adjusting for the age and infection site of patients.
conclusionThe data indicated that a significant proportion of children with traumatic and chronic OM suffered surgical intervention, although hematogenous infections remain the predominant type. Meanwhile, the infection cure was often achievable. However, clinicians should still be aware of the potential sequelae and related risk factors following surgical treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.