Evidence map›Paper›PMID 41120974›Full record

ArticleBMC pediatrics2025

Unintentional boric acid exposure: a case report and boron level monitoring.

Giordano Spacco, Valeria M Petrolini, Azzurra Schicchi, Anna Ronchi, Lucia Bernasconi, Emanuela Piccotti, Carla Debbia

Abstract readCase Reports
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Giordano Spacco *Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy.
Valeria M Petrolini *Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Via Salvatore Maugeri, 10, , 27100, Italy.
Azzurra SchicchiPavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Via Salvatore Maugeri, 10, , 27100, Italy. azzurra.schicchi@icsmaugeri.it.
Anna RonchiPavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Via Salvatore Maugeri, 10, , 27100, Italy.
Lucia BernasconiPavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab, Toxicology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Via Salvatore Maugeri, 10, , 27100, Italy.
Emanuela PiccottiEmergency department IRCCS "Giannina Gaslini" Institute for Children, Genova, Italy.
Carla DebbiaEmergency department IRCCS "Giannina Gaslini" Institute for Children, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoric acid (BA) is found in various household products. Paediatric intoxication via unusual routes remains a concern. This case report describes an 8-year-old boy who ingested BA through contaminated pasta water, with documented blood and urine boron levels. CASE PRESENTATION: An 8-year-old boy consumed homemade pasta prepared with water inadvertently contaminated with a 3% BA solution (estimated intake: 2.7-8.1 g). He presented with nausea and abdominal pain. On admission, routine blood and urine analyses revealed normal creatinine and urea levels. He was admitted for observation, intravenous fluid therapy, and monitoring of boron levels. The patient experienced one episode of vomiting and headache, which resolved with acetaminophen. Serial blood and urine boron levels were measured. The patient's initial plasma boron concentration was 16.5 mg/L, decreasing significantly within 24 h, consistent with BA's pharmacokinetics. Despite the estimated BA intake, the patient remained largely asymptomatic after the initial episode. Follow-up tests one-month post-discharge were normal.

conclusionsThis case highlights the potential for accidental BA ingestion in children and emphasizes the importance of prompt recognition and supportive treatment with intravenous fluids. While blood boron levels can confirm exposure and elimination, correlation with clinical manifestations requires further study. Ingestion of BA doses exceeding 3 g warrants immediate hyperhydration and monitoring. BA is readily absorbed, with renal excretion being the primary route of elimination. Prompt hydration is crucial. A one-month follow-up with clinical evaluation and renal function tests appears sufficient for asymptomatic patients. Further research is needed to better define the toxic dose of BA and its clinical correlation.

Indexed as

Boric AcidsBoronChildHumansMaleboric acidBoric AcidsBoron

Identifiers

PMID41120974
PMCPMC12539190

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