Evidence map›Paper›PMID 41120948›Full record

ArticleBMC infectious diseases2025

Mycobacterium farcinogenes-induced lymphadenitis in a pediatric patient: a case report.

Xingxin Liu, Yongmei Jiang, Liting Liang, Wei Zhou, Linghan Kuang, Jiaji Ling, Wenjing Wu, Ziyi Yan, Jingjing Luo

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Feline Cutaneous Mycobacteriosis Caused byAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xingxin LiuDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Yongmei JiangDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Liting LiangDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Wei ZhouDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Linghan KuangDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Jiaji LingDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Wenjing WuDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Ziyi YanDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China.
Jingjing LuoDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, o.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, China. 280988541@qq.com.

Funding

National Natural Science Foundation of China No.82300015Science and Technology Department of Sichuan Province No. 2024NSFSC1942, 2025ZNSFSC1740 and 2024NSFSC1555Sub-project under the special project "Reproductive Health and Health Security for Women and Children" of the National Key Research and Development Program of China No.2024YFC2707400
6 · The paper itself

Abstract

backgroundMycobacterium farcinogenes is primarily associated with bovine farcy and rarely infects humans. This report presents the first documented case of a 6-year-old girl diagnosed with lymphadenitis caused by Mycobacterium farcinogenes, resulting from a left submandibular mass. The case highlights the importance of maintaining vigilance for such infections, even in immunocompetent children. CASE PRESENTATION: A 6-year-old girl was hospitalized with a complaint of a “left submandibular mass for nearly 3 months.” Surgical biopsy and subsequent tissue culture confirmed the presence of Mycobacterium farcinogenes. Postoperatively, the patient was treated with a combination of clarithromycin and rifampicin, leading to substantial symptom resolution. She was discharged in stable condition 10 days after surgery. Following discharge, the patient continued the antibiotic regimen for an additional 6 months, with long-term follow-up at 9 months confirming sustained remission without recurrence.

conclusionThis is the first report documenting the isolation of Mycobacterium farcinogenes from the pus of a child with lymphadenitis. The findings suggest that Mycobacterium farcinogenes should be recognized as a possible causative agent of skin and lymph node infections, even in children with intact immune systems. Successful treatment requires thorough surgical debridement accompanied by long-term targeted antibiotic therapy, which proved effective in this case.

Indexed as

LymphadenitisMycobacterium Infections, NontuberculousAnti-Bacterial AgentsChildClarithromycinFemaleHumansRifampinTreatment OutcomeAnti-Bacterial AgentsClarithromycinRifampinCase reportMALDI-TOF MSMycobacterium farcinogenesNon-tuberculous mycobacteriaPediatric lymphadenitis

Identifiers

PMID41120948
PMCPMC12538834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.