Evidence map›Paper›PMID 41120933›Full record

Trial reportBMC anesthesiology2025

Ultrasound-guided erector spinae plane block versus rhomboid intercostal sub-serratus plane block for postoperative analgesia in open radical nephrectomy: a randomized clinical study.

Doaa Abd Eltwab, Sayed M Abed, Ahmad Saad, Maha A Abdel Aliem, Khaled A Elsamahy, Fatma H Elshamy, Ahmed F Gad, Walaa Y Elsabeeny

Registry-linked trialAbstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05822011 (Ultrasound Guided Rhomboid Intercostal Subserratus Plane Block Versus Erector Spinae Plane Block in Open Nephrectomy. Randomized Controlled Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05822011 nacompletednot on this map

Ultrasound Guided Rhomboid Intercostal Subserratus Plane Block Versus Erector Spinae Plane Block in Open Nephrectomy. Randomized Controlled Study

TypeinterventionalSponsorCairo UniversityRan2023 to 2025Enrolled42ConditionsPost Operative PainArmsRhomboid intercostal subserratus plane block, Erector spinae plane block
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Doaa Abd EltwabDepartment of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo, 11796, Egypt.
Sayed M AbedDepartment of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo, 11796, Egypt.
Ahmad SaadDepartment of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo, 11796, Egypt.
Maha A Abdel AliemDepartment of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo, 11796, Egypt.
Khaled A ElsamahyDepartment of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo, 11796, Egypt.
Fatma H ElshamyDepartment of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo, 11796, Egypt.
Ahmed F GadDepartment of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo, 11796, Egypt.
Walaa Y ElsabeenyDepartment of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo, 11796, Egypt. walaa.elsabeeny@nci.cu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOpen radical nephrectomy often results in significant acute postoperative pain. Regional anesthesia offers an alternative analgesic approach in these situations. This study aims to assess and compare the effectiveness of ultrasound-guided rhomboid intercostal sub-serratus (RISS) block with Erector Spinae Plane Block (ESPB) in patients undergoing open radical nephrectomy.

methodsThis randomized clinical trial included 42 patients scheduled for open radical nephrectomy (RN). Patients were randomly assigned to one of two groups: the ESPB Group (n = 21), which received an ESPB with 30 ml of bupivacaine 0.25%, or the RISS Group (n = 21), which received a RISS block with 30 ml bupivacaine 0.25%. Total morphine consumption was set as the primary outcome while pain scores, perioperative hemodynamics and time to postoperative analgesia were considered as secondary outcomes.

resultsTotal morphine consumption within the first 24 postoperative hours was significantly lower for the ESPB group (16.4 ± 2.5 mg) compared to the RISS group (18.2 ± 1.8 mg), p = 0.011. VAS pain scores at rest were significantly lower in the ESPB group at 12 and 18 h (p = 0.002, p = 0.018) respectively. VAS scores with movement were significantly lower for the ESPB group at 8 h,12 h, and 18 h (p = 0.011, p = 0.001, and p = 0.018 respectively). The first time to receive postoperative analgesia was significantly longer in the ESPB group (7.3 ± 2.1 h) than in the RISS group (6.0 ± 2.1 h), p = 0.048. Both groups were comparable in the number of PCA boluses, the number of patients requiring intraoperative fentanyl increments, or recovery time.

conclusionUltrasound-guided ESPB provides slightly superior postoperative analgesia compared with RISS block in patients undergoing open radical nephrectomy via subcostal anterior incision for renal malignancies.

trial registrationThe trial was registered at Clinical Trials.gov. https://clinicaltrials.gov/study/NCT05822011 , trial ID (NCT05822011, 14 March 2023).

Indexed as

NephrectomyNerve BlockPostoperative PainUltrasonography, InterventionalAgedAnalgesics, OpioidAnesthetics, LocalBupivacaineFemaleHumansMaleMiddle AgedMorphinePain MeasurementParaspinal MusclesAnalgesics, OpioidAnesthetics, LocalBupivacaineMorphineAnalgesiaMorphineNephrectomyRegional anesthesia

Identifiers

PMID41120933
PMCPMC12542437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.