ArticleBMC pediatrics2025
Comparing the effect of remimazolam and propofol anesthesia on extubation time, hospital stay and psychological wellbeing post pediatric tonsillectomy and adenoidectomy.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Advantages of Remimazolam in Pediatric Anesthesia: A Narrative Review.Children (Basel, Switzerland) · 2026Review
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic tonsillitis and adenoid hypertrophy can significantly impact children's growth and development, making surgical intervention necessary. The choice of anesthesia is critical to ensuring both safety and efficacy during such procedures. Propofol and remimazolam are commonly used anesthetic agents, but their relative advantages in pediatric surgery have not been thoroughly explored. Therefore, this study examines the comparative effects of propofol and remimazolam anesthesia in pediatric patients undergoing tonsillectomy and adenoidectomy. We hypothesized that remimazolam would result in more stable intraoperative vital signs, faster postoperative recovery, and fewer adverse events than propofol.
methodsIn this comparative study, 193 pediatric patients from the Maternal and Child Health Hospital of Hubei Province in Wuhan, China, were enrolled between October 2021 and October 2023. Of these, 83 received propofol anesthesia and 110 received remimazolam anesthesia. The study assessed hemodynamic parameters, including heart rate, blood pressure, and oxygen saturation, at several time points, along with various recovery outcomes such as surgical duration, time to spontaneous respiratory recovery, extubation, and postoperative hospital stay. Moreover, post-extubation coughing, CHEOPS pain score, Ramsay score, Sedation-Agitation Scale (SAS) and rate of adverse reactions were compared between the two groups of pediatric patients subsequent to surgery.
resultsThe differences in HR, SBP, DBP, and SpO
conclusionIn conclusion, remimazolam offers superior stability, faster recovery, and fewer complications compared to propofol. These findings support the use of remimazolam as a safer and more efficient anesthetic agent for pediatric tonsillectomy and adenoidectomy.
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