Evidence map›Paper›PMID 41120883›Full record

ArticleBMC anesthesiology2025

Variations of nociception level (NOL

Julia Heiden, Jonas Hoefermann, Katharina Hoeter, Jens Kamuf, Robert Kuchen, Miriam Renz, Robert Ruemmler, Alexander Ziebart

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia HeidenDepartment of Anaesthesiology, University Medical Center Mainz, Mainz, Germany.
Jonas HoefermannDepartment of Anaesthesiology, University Medical Center Mainz, Mainz, Germany.
Katharina HoeterDepartment of Anaesthesiology, University Medical Center Mainz, Mainz, Germany.
Jens KamufDepartment of Anaesthesiology, University Medical Center Mainz, Mainz, Germany.
Robert KuchenInstitute for Medical Statistics, Epidemiology and Informatics, University Medical Center Mainz, Mainz, Germany.
Miriam RenzDepartment of Anaesthesiology, University Medical Center Mainz, Mainz, Germany.
Robert Ruemmler *Department of Anaesthesiology, University Medical Center Mainz, Mainz, Germany.
Alexander Ziebart *Department of Anaesthesiology, University Medical Center Mainz, Mainz, Germany. alexander.ziebart@unimedizin-mainz.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInadequate analgesia during anaesthesia is associated with a range of complications. While anaesthesiologists routinely monitor the depth of anaesthesia and neuromuscular blockade, no system currently in routine clinical use provides an objective assessment of adequacy of anti-nociception. Although various monitoring systems have been developed in recent years, their impact on the optimization of analgesic therapy remains uncertain. Moreover, the influence of perioperative surgical and non-surgical procedures and events on the measured parameters is not yet fully understood. Nonetheless, this knowledge is essential for the accurate interpretation and effective clinical application of these emerging monitoring technologies.

methodsThirty-three patients undergoing robot-assisted laparoscopic prostatectomy using the da Vinci Surgical System were retrospectively analysed. At five specific stimuli (gastric tube placement, urinary catheter placement, initiation of capnoperitoneum, transition to the steep Trendelenburg position and administration of sufentanil) NOL

resultsWe noticed a significant increase in NOL

conclusionThe NOL

Indexed as

LaparoscopyMonitoring, IntraoperativeNociceptionProstatectomyRobotic Surgical ProceduresAgedHumansMaleMiddle AgedRetrospective StudiesAnaesthesiaNociception level indexNociception monitorNon-invasive monitoringRobot-assisted surgery

Identifiers

PMID41120883
PMCPMC12542441

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.