Evidence map›Paper›PMID 41120812›Full record

ArticleJournal of the American Heart Association2025

Subclinical Cardiac Dysfunction in Women With Prior Gestational Diabetes: The Hispanic Community Study/Study of Latinos.

Eric K Broni, Lisa D Levine, Jennifer Lewey, Ravi Retnakaran, Allison G Hays, Justin B Echouffo-Tcheugui

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eric K BroniPregnancy and Perinatal Research Center University of Pennsylvania Perelman School of Medicine Philadelphia PA.ORCID 0009-0007-4074-5751
Lisa D LevinePregnancy and Perinatal Research Center University of Pennsylvania Perelman School of Medicine Philadelphia PA.ORCID 0000-0002-6811-7980
Jennifer LeweyDivision of Cardiology Department of Medicine University of Pennsylvania Perelman School of Medicine Philadelphia PA.ORCID 0000-0003-3483-5527
Ravi RetnakaranDivision of Endocrinology and Metabolism, Department of Medicine University of Toronto Toronto ON Canada.ORCID 0000-0003-1989-027X
Allison G HaysDivision of Cardiology, Department of Medicine Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0003-2138-1589
Justin B Echouffo-TcheuguiDivision of Endocrinology, Diabetes & Metabolism Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0002-8460-1617

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational diabetes (GD) is associated with heart failure risk. However, the association of GD and postpartum early stages of myocardial dysfunction (a robust predictor of heart failure) as assessed by imaging has seldom been examined, especially among Hispanic women, who represent the fastest-growing ethnic minority population and have the highest prevalence of GD in US women.

methodsWe examined Hispanic women recruited to the Hispanic Community Study/Study of Latinos cohort, who reported at least 1 prior pregnancy and GD history at either visit 1 (2008-2011) or visit 2 (2014-2017) and echocardiographic assessments at visit 2. We used multivariable linear and logistic regression models to evaluate the associations between GD history and echocardiographic parameters.

resultsAmong 2894 participants (mean age 53±9 years), 9.3% (n=270) had a GD history. After adjusting for cardiovascular disease risk factors, including current diabetes status, Hispanic women with GD history had higher mean adjusted left ventricular relative wall thickness (β=0.01 [95% CI, 0.00-0.02]), lateral peak early mitral inflow velocity to early diastolic velocity of the mitral annulus ratio (β=0.49 [95% CI, 0.09-0.89]), abnormal left ventricular diastolic function (adjusted odds ratio, 1.41 [95% CI, 1.04-1.91]), and lower mean adjusted left ventricular end-diastolic diameter (β=-0.07 [95% CI, -0.12 to -0.02]) compared with those without prior GD history. Similar associations were observed in results stratified by the most recent glycemic status.

conclusionsHistory of GD was associated with a higher frequency and severity of myocardial diastolic abnormalities. Echocardiographic-based screening for myocardial dysfunction in women with GD history has the potential to help avert overt cardiovascular disease in this high-risk population.

Indexed as

Diabetes, GestationalHispanic or LatinoVentricular Dysfunction, LeftVentricular Function, LeftAdultAsymptomatic DiseasesEchocardiographyFemaleHumansMiddle AgedPregnancyPrevalenceRisk FactorsUnited StatesWhiteechocardiographygestational diabetessubclinical cardiovascular disease

Identifiers

PMID41120812
PMCPMC12684540

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.