Evidence map›Paper›PMID 41120616›Full record

ArticlePediatric surgery international2025

Thoracoscopic hiatoplasty in congenital diaphragmatic hernia is safe and less invasive: a prospective propensity-matched short-term study.

Michaela Klinke, Richard Martel, Christel Weiß, Christoph Mohr, Thomas Schaible, Nina Dietze, Jana Hoffmann, Michael Boettcher, Julia Elrod

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Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Michaela KlinkeDepartment of Pediatric Surgery, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. Michaela.KlinkePetrowsky@medma.uni-heidelberg.de.
Richard MartelDepartment of Pediatric Surgery, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Christel WeißDepartment of Medical Statistics and Biomathematics, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, Mannheim, Germany.
Christoph MohrDepartment of Pediatric Surgery, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Thomas SchaibleDepartment of Neonatology, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Nina DietzeDepartment of Pediatric Surgery, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Jana HoffmannDepartment of Pediatric Surgery, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Michael Boettcher *Department of Pediatric Surgery, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Julia Elrod *Department of Pediatric Surgery, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCongenital diaphragmatic hernia (CDH) is a condition linked to neonatal morbidity, mortality, and gastroesophageal reflux. Traditional hiatoplasty via laparotomy or laparoscopy is complicated by abdominal adhesions from previous CDH repair. A thoracoscopic technique, avoiding abdominal preparation, was introduced to address these issues. This study evaluates its safety and efficacy in children with CDH.

methodsA prospective, propensity-matched study was conducted on pediatric patients undergoing thoracoscopic hiatoplasty (TH) or hiatoplasty via laparotomy for CDH at University Hospital Mannheim (2013-2024). Outcomes included operative time, ICU LOS and overall hospital stay (LOS), complication rates, and recovery, assessed via parent-reported questionnaires.

results57 children underwent hiatoplasty via laparotomy, while 12 had TH. Propensity matching yielded 27 patients (laparotomy n = 19, TH n = 8). TH showed shorter operative time (71.5 vs 190.5 min; p = 0.0018), reduced ICU LOS (0.1 ± 0.3 vs 1.6 ± 4.0 days; p = 0.0002), and shorter overall LOS (2.4 ± 1.1 vs 13.2 ± 6.1 days; p < 0.0001). Complications were fewer (p = 0.0022), and dietary progression improved (p = 0.0181), with a trend toward earlier sports resumption (p = 0.0545). Follow-up duration was markedly shorter in the TH group (median 109 days [IQR 70-151] vs. 1465 days [IQR 924-2390], p = 0.0041).

conclusionTH is a safe, effective antireflux therapy for CDH, offering better recovery and fewer complications. Interpretation is limited by the shorter follow-up in the thoracoscopic group. Long-term randomized trials are needed to confirm these results.

Indexed as

Hernias, Diaphragmatic, CongenitalHerniorrhaphyThoracoscopyFemaleHumansInfantInfant, NewbornLaparotomyLength of StayMaleOperative TimePostoperative ComplicationsPropensity ScoreProspective StudiesTreatment OutcomeAntirefluxCDHCongenital diaphragmatic herniaHiatoplastyMinimal invasive surgeryThoracoscopy

Identifiers

PMID41120616
PMCPMC12540631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.