Evidence map›Paper›PMID 41120555›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2026

A prospective randomized crossover trial studying the effects of maternal heartbeat and voice sounds on resting energy expenditure in preterm infants.

Gurpreet Kaur, Sean M Bailey, Stacey Schneider, Elena Savvides, Heather Howell, Bridget Kiernan, Rishika Sharma, Pradeep Mally, Sourabh Verma

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects of Maternal Heartbeat Exposure on Neonatal Autonomic Regulation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gurpreet KaurDivision of Neonatology, Hassenfeld Children's Hospital at NYU Langone, New York City, NY, USA.
Sean M BaileyDivision of Neonatology, Hassenfeld Children's Hospital at NYU Langone, New York City, NY, USA.
Stacey SchneiderDivision of Therapeutic Recreations, Child Life and Creative Arts Therapies, Sala Institute for Child & Family Centered Care, Hassenfeld Children's Hospital at NYU Langone, New York City, NY, USA.
Elena SavvidesDivision of Therapeutic Recreations, Child Life and Creative Arts Therapies, Sala Institute for Child & Family Centered Care, Hassenfeld Children's Hospital at NYU Langone, New York City, NY, USA.
Heather HowellDivision of Neonatology, Hassenfeld Children's Hospital at NYU Langone, New York City, NY, USA.
Bridget KiernanDivision of Pediatric Gastroenterology, Hassenfeld Children's Hospital at NYU Langone, New York City, NY, USA.
Rishika SharmaDepartment of Pediatrics, Family Healthcare Network, Visalia, CA, USA.
Pradeep MallyDivision of Neonatology, Hassenfeld Children's Hospital at NYU Langone, New York City, NY, USA.
Sourabh VermaDivision of Neonatology, Hassenfeld Children's Hospital at NYU Langone, New York City, NY, USA. sourabh.verma@nyulangone.org.ORCID http://orcid.org/0000-0002-5584-7773

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare resting energy expenditure (REE) among premature infants exposed to recorded maternal heartbeat and voice (MHV) vs. ambient noise. STUDY

designA prospective, randomized crossover pilot trial evaluating the effect of MHV on REE using indirect calorimetry in hemodynamically stable premature infants born at 26-34 weeks' gestation. MHV recordings were digitally overlapped, and exposure sequence was randomized.

resultAmong 34 measurements from seventeen subjects, REE was significantly lower during MHV exposure compared to ambient noise (61.4 ± 10.3 vs. 70.9 ± 10.3 kcal/kg/day, p = 0.0001). Mean heart rate was also significantly lower with MHV (144 ± 13 vs. 150 ± 11 bpm, p = 0.028), with no differences in other vital signs.

conclusionREE of premature infants decreased during exposure to MHV when compared with ambient noise. MHV may serve as a potential noninvasive therapeutic intervention to improve metabolic efficiency in premature infants, potentially helping with improved growth.

Indexed as

Energy MetabolismHeart RateInfant, PrematureNoiseVoiceCalorimetry, IndirectCross-Over StudiesFemaleHumansInfant, NewbornMalePilot ProjectsPregnancyProspective Studies

Identifiers

PMID41120555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.