Evidence map›Paper›PMID 41120433›Full record

ArticleScientific reports2025

Cinnamaldehyde as a dietary modulator of gut microbiota and growth in broilers under low-protein feeding conditions.

Xinzhu Chen, Wen Yue, Zhongrong Li, Weigang Jin, Haihong Lin, Jing Liu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinzhu ChenFujian Academy of Agricultural Sciences/Fujian Key Laboratory of Animal Genetics and Breeding, Institute of Animal Husbandry and Veterinary Medicine, Fuzhou, 350013, China. 010622051@163.com.
Wen YueFujian Academy of Agricultural Sciences/Fujian Key Laboratory of Animal Genetics and Breeding, Institute of Animal Husbandry and Veterinary Medicine, Fuzhou, 350013, China.
Zhongrong LiFujian Academy of Agricultural Sciences/Fujian Key Laboratory of Animal Genetics and Breeding, Institute of Animal Husbandry and Veterinary Medicine, Fuzhou, 350013, China.
Weigang JinPostdoctoral Programme of Fujian Fuda Biotech Co., Ltd, Fuzhou, 350013, China.
Haihong LinPostdoctoral Programme of Fujian Fuda Biotech Co., Ltd, Fuzhou, 350013, China.
Jing LiuFujian Academy of Agricultural Sciences/Fujian Key Laboratory of Animal Genetics and Breeding, Institute of Animal Husbandry and Veterinary Medicine, Fuzhou, 350013, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cinnamaldehyde (CM), recognized for its antimicrobial and anti-inflammatory capabilities, is increasingly valued as an animal feed additive, primarily for its potential to augment gut health and promote general animal welfare. However, our understanding of CM as a feed additive to a low-protein diet on broilers' growth performance and microbial composition is still limited. To investigate the effect of CM supplementation on the growth performance and microbial composition of broilers within a low-protein diet administration, we employed a combination of serum biochemical tests, growth parameters, and high-throughput sequencing (HTS) techniques. The results indicated a significant increase in body weight (N = 40) and feed efficiency ratio (N = 40; P < 0.05) following CM administration. Meanwhile, the microbial taxonomic analysis found that feeding CM increased the richness of Firmicutes, Faecalibacterium, and Lactobacillus while diminishing the diversity of Bacteroidetes, Actinobacteria, Oscillospira, and Bacteroides. Besides, serum biochemical tests revealed that the CM administration significantly increased the immunity factors (IgA and IgE) than the low-protein (LP) group. These findings offer crucial insights into the interplay between gut microbiota and animal growth performance, elucidating the role of CM supplementation in the context of low-protein diets.

Indexed as

AcroleinChickensDiet, Protein-RestrictedGastrointestinal MicrobiomeAnimal FeedAnimalsDietary SupplementsAcroleincinnamaldehydeBroiler chickensCinnamaldehydeGrowth performanceIntestinal microbial compositionLow-protein diet

Identifiers

PMID41120433
PMCPMC12540810

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.