ArticleNature communications2025
Differential topographic organization and retinal inheritance of direction and orientation selectivity in the visual thalamus.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Spatial biases in visual feature representation of mouse dorsal lateral geniculate nucleus boutons.iScience · 2026Article
- Differential topographic organization and retinal inheritance of direction and orientation selectivity in the visual thalamus.Nature communications · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The lateral geniculate nucleus (LGN) of the thalamus, a major retinal target, processes and relays visual information, including direction selectivity (DS) and orientation selectivity (OS). However, the organization of DS and OS in the LGN, including the extent to which the information is directly inherited from the retina or generated within the LGN, remains poorly understood. Using high-density recordings from across the mouse LGN, we reveal two distinct organization patterns: LGN DS responses are scarce in the central visual field and are topographically aligned to translatory optic flow dynamics around it, whereas OS responses span the visual field. In transgenic mice lacking retinal DS, we find that only LGN DS, but not LGN OS responses are eliminated. Our results suggest that LGN DS is inherited from the retina, although the retinogeniculate transfer is topography-dependent and potentially optimized for representations that support visually-guided behaviors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.