Evidence map›Paper›PMID 41120327›Full record

ArticleNature communications2025

Real-time, high-throughput super-resolution microscopy via panoramic integration.

Kyungduck Yoon, Hansol Yoon, Kidan Tadesse, Zhi Ling, Biagio Mandracchia, Sayantan Datta, G Ozan Bozdag, Anthony J Burnetti, William C Ratcliff, Shu Jia

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kyungduck Yoon *Laboratory for Systems Biophotonics, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-3106-9735
Hansol Yoon *Laboratory for Systems Biophotonics, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-3410-927X
Kidan TadesseLaboratory for Systems Biophotonics, Georgia Institute of Technology, Atlanta, GA, USA.
Zhi LingLaboratory for Systems Biophotonics, Georgia Institute of Technology, Atlanta, GA, USA.
Biagio MandracchiaLaboratory for Systems Biophotonics, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-4583-4733
Sayantan DattaSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-0529-4402
G Ozan BozdagSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.
Anthony J BurnettiSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0003-3856-8251
William C RatcliffSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-6837-8355
Shu JiaLaboratory for Systems Biophotonics, Georgia Institute of Technology, Atlanta, GA, USA. shu.jia@gatech.edu.ORCID http://orcid.org/0000-0001-6854-7537

Funding

Toward Systems Biophotonics: Imaging Biology across High Dimensions and ScalesR35GM124846 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI Shu Jia · 2017 to 2026
$4.0M
Using directed evolution to study the origins of multicellular development.R35GM138030 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI William Croft Ratcliff · 2020 to 2026
$2.8M
National Science Foundation (NSF) DBI2145235National Science Foundation (NSF) EFMA1830941NIGMS NIH HHS R35 GM124846NIGMS NIH HHS R35 GM138030U.S. Department of Health & Human Services | National Institutes of Health (NIH) R35GM124846U.S. Department of Health & Human Services | National Institutes of Health (NIH) R35-GM138030
6 · The paper itself

Abstract

We introduce super-resolution panoramic integration (SPI), an on-the-fly microscopy technique enabling instantaneous generation of subdiffractional images concurrently with scalable, high-throughput screening. SPI leverages multifocal optical rescaling, high-content sweeping, and synchronized line-scan readout while preserving minimal post-processing and compatibility with epi-fluorescence settings. We demonstrate SPI for various subcellular and populational morphology, function, and heterogeneity. This versatile platform offers a practical pathway toward biological insights beyond traditional optical and computational constraints.

Indexed as

High-Throughput Screening AssaysMicroscopyAnimalsHumansImage Processing, Computer-AssistedMicroscopy, Fluorescence

Identifiers

PMID41120327
PMCPMC12541073

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.