Evidence map›Paper›PMID 41120194›Full record

ArticleArchives of disease in childhood2026

Economic modelling of providing 'spare' adrenaline autoinjectors to all schools to improve the management of anaphylaxis.

Paul J Turner, Andrew Bright, Louise J Michaelis, Jennifer K Quint

Abstract read
In one paragraph

Article in Archives of disease in childhood, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Adrenaline Auto-Injector Prescribing in Primary Care in England: An Analysis of Non-Standard Dosing.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul J TurnerNational Heart & Lung Institute, Imperial College London, London, UK p.turner@imperial.ac.uk.ORCID 0000-0001-9862-5161
Andrew BrightGateshead Health NHS Foundation Trust, Gateshead, UK.ORCID 0000-0003-2511-7654
Louise J MichaelisPaediatric Immunology and Allergy, Great North Children's Hospital, Newcastle Upon Tyne, UK.ORCID 0000-0001-8229-154X
Jennifer K QuintSchool of Public Health, Imperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyse NHS health datasets to estimate the cost of providing emergency adrenaline [epinephrine] autoinjectors (AAIs) to school pupils on a named-patient basis to leave on school premises versus providing 'spare' AAIs to schools which can be used for any school pupil.

designRetrospective cohort study.

settingEnglish primary electronic health data from the Clinical Practice Research Datalink (CPRD) and English prescriptions data from the NHS Business Services Authority.

participantsSchool-aged children in England.

main outcome measures(1) Proportion of school children with food allergy prescribed AAI; (2) cost of providing more than two AAIs to individual pupils mapped to integrated care boards (ICBs) in England compared with the cost of providing four spare AAIs to every school for the academic year 2023/24.

results44% of school-aged children in the CPRD had at least one AAI prescription and only 34% had repeat AAIs prescribed. In pupils with previous anaphylaxis, rates were 59% and 44%, respectively. During the academic year 2023/24, 63% of pupils were dispensed more than two AAIs at an estimated cost of over £9 million. The estimated cost of providing spare AAIs to every school was £4.5 million. If spare AAIs were to replace the supply of named-patient AAIs exclusively to leave on school premises, this would represent a potential cost-saving of at least £4.6 million or 25% of the total national expenditure for AAIs.

conclusionsUnder half of children at risk of anaphylaxis are prescribed AAIs. Providing spare AAIs to all schools (at no cost to the school) would be a cost-neutral strategy for the vast majority of ICBs and one that is likely to improve emergency access to AAIs and therefore safety.

Indexed as

AnaphylaxisEpinephrineSchool Health ServicesAdolescentChildEnglandFemaleFood HypersensitivityHumansInjections, IntramuscularMaleModels, EconomicRetrospective StudiesSchoolsState MedicineEpinephrineAllergy and ImmunologyChild WelfareEmergency CareEpidemiologyHealth Care Economics and Organizations

Identifiers

PMID41120194
PMCPMC13018742

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.