ArticleTranslational behavioral medicine2025
The adaptation of meaning centered psychotherapy to develop RELOAD-C: a web-based tool to reduce loneliness in caregivers of persons with Alzheimer's disease and related dementias.
Article in Translational behavioral medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Generative AI as interactional infrastructure for meaning-centered care in later life.Frontiers in psychiatry · 2026Article
- Adjunctive individual meaning-centered psychotherapy plus protocolized fluoxetine for moderate-to-severe adolescent depression.Frontiers in psychiatry · 2025Article
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Authors and funding
12 authors.
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Abstract
backgroundMore than 60% of caregivers of persons with Alzheimer's disease and related dementias (AD/ADRD) are lonely. Meaning and purpose in life is associated with reduced feelings of loneliness, but has not yet been systematically fostered among caregivers of patients with AD/ADRD. Adapting meaning-centered psychotherapy (MCP), an evidence-based treatment for increasing meaning and purpose in life in cancer caregivers, might decrease loneliness in the dementia caregiver population. PURPOSE: The purpose of this manuscript is to report on the development, usability, and acceptability testing of REducing LOneliness in Alzeheimer's Disease-Care Partners (RELOAD-C), a web-based platform that features six brief videos and aims to reduce loneliness in caregivers of patients with dementia through introducing major concepts and principles adapted from meaning centered psychotherapy.
methodWithin 12 months, RELOAD-C was developed through two rounds of one-on-one interviews with 15 dementia caregivers to obtain feedback on video scripts, recording of videos, and placement of videos and written content (e.g. thought exercises) on the website. Following this, RELOAD-C underwent rigorous usability and acceptability testing by another 16 dementia caregivers.
resultsQuantitative assessments show that RELOAD-C is deemed usable by caregivers (mean = 1.69 on system usability scale, where possible range is 1-5 and lower scores indicate more favorable views of the website; and more than 90% of the usability sample correctly engaged in ≥8 of 10 discreet tasks). Qualitative data indicate acceptability of the intervention with feedback such as "love that the videos are clear and load fast."
conclusionsRELOAD-C is a web-based intervention focused on reducing loneliness in dementia caregivers. It contains six therapist-narrated videos and written content, reinforcing MCP principles. It is currently undergoing pilot testing in preparation for a large-scale randomized controlled clinical trial evaluating its efficacy in reducing loneliness in dementia caregivers.
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