Observational studyJournal of Korean medical science2025
Comparison of Cardiac Events and Survival Between Asymptomatic Diabetic and Nondiabetic Patients: Coronary CT Study.
Observational study in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01416532 (Prognostic Value of Coronary CT Angiography in Relation to Evaluation of Subclinical Coronary Atherosclerosis for Risk Stratification in Asymptomatic Individuals From ESCORT Study), which is not on this map. Not yet cited in PubMed.
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Prognostic Value of Coronary CT Angiography in Relation to Evaluation of Subclinical Coronary Atherosclerosis for Risk Stratification in Asymptomatic Individuals From ESCORT Study
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough coronary computed tomography angiography (CCTA) is useful for risk stratification in patients with diabetes, limited data is available regarding its prognostic value in asymptomatic patients with type 2 diabetes mellitus (T2DMs). Therefore, we aimed to evaluate the utility of CCTA in coronary artery disease (CAD) risk stratification in T2DMs compared to that in patients without diabetes mellitus (non-DMs).
methodsWe selected 565 T2DMs and 1,130 non-DMs using propensity score matching from the Evaluation of Subclinical Coronary atherosclerosis for Risk Stratification Using the Coronary Computed Tomography Angiography (ESCORT) study of 5,142 asymptomatic individuals. We evaluated CCTA findings and confirmed the occurrence of major adverse cardiac events (MACE; cardiac death, non-fatal myocardial infarction, and unstable angina) and total cardiac events (TCE; MACE plus coronary revascularization) during follow-up using Cox proportional hazards analysis and Kaplan-Meier survival curves.
resultsOver a median follow-up of 47 months, MACE and TCE occurred significantly more in T2DMs than in non-DMs (4.2% vs. 1.7% and 7.8% vs. 4.3%, respectively, all
conclusionWhile diabetes is an independent risk factor for CAD, its impact on survival rate varies with the severity of CAD, highlighting the value of CCTA as a prognostic tool for CAD risk stratification in asymptomatic T2DMs.
trial registrationClinicalTrials.gov Identifier: NCT01416532.
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