ReviewNeuron2026
Retrotransposons unplugged: Rewiring the nervous system and wreaking havoc.
Review in Neuron, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The retroelement-derived human protein PEG10 is a regulator of mRNA splicing in neurons.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The retrotransposons and endogenous retroviruses (ERVs) that contain long terminal repeat (LTR) sequences are a subset of transposable elements (TEs) that make up around 8% of the human genome. These retroelements (retroTEs) are derived from ancient retroviral infections or retrotransposons that have become permanently integrated into the germline and include domesticated retroTEs, such as the neuronal gene Arc. Until recently, limited tools and difficulties in mapping retroTEs have made it challenging to study these elements in detail. However, recent advances have revealed that retroTEs play a role in both human disease and physiological processes in the brain. Here, we highlight studies showing that retroTE nucleic acid and protein products perform unique functions in intercellular signaling and nervous system dysfunction. We discuss how these elements play critical roles in complex processes such as cognition and how future work will provide insight into neurological disorders.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.