ArticleNucleic acids research2026
Ribocentre-aptamer: an integrative, structure-focused database for RNA aptamers.
Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- AptViralDB: A repository of experimentally validated antiviral aptamers.Molecular therapy. Nucleic acids · 2026Review
- HURDLER: a cloning method to overcome length limits in designed repeat proteins.Nucleic acids research · 2026Article
- APDB: A Large-Scale Repository of Predicted 2D and 3D Aptamer Structures.Journal of chemical information and modeling · 2026Article
- The 2026 Nucleic Acids Research database issue and the online molecular biology database collection.Nucleic acids research · 2026Article
- Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next-Generation Diagnostics and Biosensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Funding
Abstract
RNA aptamers function as 'chemical antibodies' with advantages in binding to diverse ligands, enabling transformative applications in diagnostics, therapeutics, and biosensing. Despite these potential and existing databases, rational aptamer design is hindered by the lack of integrated resources coupling experimentally determined structural data with ligand-binding mechanisms. Here, we present Ribocentre-aptamer (https://aptamer.ribocentre.org/), a manually curated database to capture the molecular mechanism of RNA aptamer binding. Our resource systematically catalogues 191 aptamer types across 669 publications, unifying 510 sequences, 123 small-molecule ligands, and 344 protein ligands with experimentally resolved secondary/tertiary structures, ligand-binding pockets, affinity metrics, and functional annotations. Ribocentre-aptamer aims to bridge molecular mechanism discovery with translational engineering, providing an indispensable platform for advancing aptamer science.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.