ReviewScience progress
Research progress on the relationship between nanocrystals and calcium oxalate stones.
Review in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
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Abstract
Urological stones are the common urological diseases in clinical practice. So far, the mechanisms of kidney stone formation still remain unclear. Among all of the mechanisms, the supersaturated crystallization theory focuses on the microcrystal size of stones. However, there are few researches on the formation mechanism of stones in nanoscale. This narrative review summarizes the current mainstream mechanisms of kidney stone formation. It also discusses the relationship between calcium oxalate (CaOx) nanocrystals and the formation of kidney stones from the perspective of the physicochemical properties of the nanocrystals. To further explore the role of CaOx nanocrystals in the formation of CaOx, this review lists some convenient and reliable methods for tracking nanocrystals. Currently, in addition to mainstream treatments like potassium sodium hydrogen citrate and thiazide diuretics, some researches indicate that polysaccharide drugs, selenium nanoparticles, and dietary can inhibit the formation of nanocrystals, ultimately preventing the formation of CaOx stones.
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