Evidence map›Paper›PMID 41118391›Full record

SynthesisPloS one2025

Prevalence of opportunistic bacterial infections (tuberculosis and pneumonia) among people with HIV in Ethiopia: Systematic review and meta-analysis.

Aleka Aemiro, Abayeneh Girma, Getachew Alamnie, Demsew Beletew, Amere Genet

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aleka AemiroDepartment of Biology, College of Natural and Computational Sciences, Mekdela Amba University, Tulu Awuliya, Ethiopia.
Abayeneh GirmaDepartment of Biology, College of Natural and Computational Sciences, Mekdela Amba University, Tulu Awuliya, Ethiopia.ORCID https://orcid.org/0000-0001-6155-315X
Getachew AlamnieDepartment of Biology, College of Natural and Computational Sciences, Mekdela Amba University, Tulu Awuliya, Ethiopia.
Demsew BeletewDepartment of Statistics, College of Natural and Computational Sciences, Mekdela Amba University, Tulu Awuliya, Ethiopia.ORCID https://orcid.org/0009-0002-5996-443X
Amere GenetDepartment of Biology, College of Natural and Computational Sciences, Mekdela Amba University, Tulu Awuliya, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndividuals with weakened immune systems, such as those living with Human Immunodeficiency Virus (HIV), are more vulnerable to opportunistic bacterial infections, which include tuberculosis and pneumonia. This systematic review and meta-analysis looked at the pooled prevalence of opportunistic bacterial infections among people living with HIV in different regions of Ethiopia.

methodsBy looking through open online databases, articles written in English were considered. Joanna Briggs Institute's critical appraisal tool for prevalence study was used to check the quality of each article. Inverse variance (I2), sensitivity analysis, funnel plot, and Egger's regression tests were used to check heterogeneity and publication bias. Because of a high heterogeneity, a random-effects model was used to estimate the pooled prevalence of opportunistic bacterial infections among people living with HIV.

resultsAbout 18.06% (1824/9651) with (95% CI: 14.09-22.02) of the pooled population had opportunistic tuberculosis from 20 studies included, while from 16 included studies, the pneumonia infection was 11.64% (1040/8095/) with (95% CI: 8.45-14.83).

conclusionThe prevalence of tuberculosis and pneumonia among people living with HIV in Ethiopia is high. Therefore, policymakers and health planners should put a great deal of emphasis on the implementation of relevant prevention and control measures. REGISTRATION: The review was registered in the International Prospective Register of Systematic Reviews (PROSPERO) with the registration number "CRD42024587645", on September 17, 2024.

Indexed as

AIDS-Related Opportunistic InfectionsHIV InfectionsPneumoniaTuberculosisEthiopiaHumansPrevalence

Identifiers

PMID41118391
PMCPMC12539741

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.