Evidence map›Paper›PMID 41118266›Full record

ArticleJournal of the American Chemical Society2025

Intracellular Peptide N-Myristoylation for Cancer Cell Ferroptosis without Acquired Resistance.

Qiuxin Zhang, Weiyi Tan, Isabela Ashton-Rickardt, William Lau, Linrui Zou, Bing Xu

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation.Angewandte Chemie (International ed. in English) · 2026
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qiuxin ZhangDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02454, United States.ORCID 0000-0002-8659-3569
Weiyi TanDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02454, United States.ORCID 0000-0001-5316-8278
Isabela Ashton-RickardtDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02454, United States.
William LauDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02454, United States.
Linrui ZouDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02454, United States.
Bing XuDepartment of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02454, United States.ORCID 0000-0002-4639-387X

Funding

Subcellular Enzyme-instructed self-assembly for molecular anticancer nanomedicinesR01CA142746 · NCI · BRANDEIS UNIVERSITY · PI Bing Xu · 2010 to 2026
$6.4M
NCI NIH HHS R01 CA142746
6 · The paper itself

Abstract

N-Myristoylation, a well-known protein lipidation process, has yet to be explored for in situ peptide lipidation. Here, we report intracellular peptide N-myristoylation for potently inhibiting cancer cells. A self-assembling d-peptide, Gbb-NBD (

Indexed as

Antineoplastic AgentsFerroptosisMyristic AcidPeptidesCell Line, TumorHumansAntineoplastic AgentsMyristic AcidPeptides

Identifiers

PMID41118266
PMCPMC12593337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.