Evidence map›Paper›PMID 41118165›Full record

ArticleJAMA network open2025

Diabetic Retinopathy Screening Among Federally Qualified Health Center Patients Using Point-of-Care AI: DRES-POCAI: A Trial Protocol.

Edgar A Diaz, Marva L Seifert, Vida Gruning, Nicole A Stadnick, Elizabeth Lugo-Butler, Ariel N Servin, Christian I Rodríguez-Rosales, Carrie Geremia, Chaithanya Ramachandra, Malavika Bhaskaranand and 6 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06721351 (Diabetic Retinopathy Screening Point-of-Care Artificial Intelligence -DRES-POCAI), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06721351 naactive not recruitingnot on this map

Diabetic Retinopathy Screening Point-of-Care Artificial Intelligence -DRES-POCAI: AI - Clinical Intervention at San Ysidro Health

TypeinterventionalSponsorCentro De Salud La Comunidad De San Ysidro Inc DBA: San Ysidro HealthRan2024 to 2026Enrolled548ConditionsDiabetic Retinopathy (DR)ArmsDiabetic Retinopathy screening Point of Care Artificial Intelligence
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Edgar A DiazSan Ysidro Health, San Diego, California.
Marva L SeifertDepartment of Medicine, University of California San Diego, La Jolla.
Vida GruningSan Ysidro Health, San Diego, California.
Nicole A StadnickDepartment of Psychiatry, University of California San Diego, La Jolla.
Elizabeth Lugo-ButlerSan Ysidro Health, San Diego, California.
Ariel N ServinSan Ysidro Health, San Diego, California.
Christian I Rodríguez-RosalesSan Ysidro Health, San Diego, California.
Carrie GeremiaUniversity of California San Diego Altman Clinical and Translational Research Institute Dissemination and Implementation Science Center, La Jolla.
Chaithanya RamachandraEyenuk Inc, Woodland Hills, California.
Malavika BhaskaranandEyenuk Inc, Woodland Hills, California.
Dan HowardSan Ysidro Health, San Diego, California.
Oliver SolisSan Ysidro Health, San Diego, California.
Sharon VelasquezSan Ysidro Health, San Diego, California.
Brian SnookSan Ysidro Health, San Diego, California.
Sonia TuckerSan Ysidro Health, San Diego, California.
Fatima A MuñozSan Ysidro Health, San Diego, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Diabetic retinopathy screening (DRS) rates have historically been low among underserved populations due to barriers in accessing traditional eye care. Although artificial intelligence (AI)-powered DRS provides a potential strategy to improve screening rates, its optimal integration into primary care workflows within federally qualified health centers (FQHCs) requires rigorous evaluation. The clinical workflow of the Diabetic Retinopathy Screening Point-of-Care Artificial Intelligence (DRES-POCAI) trial in FQHCs integrates AI-powered DRS with electronic health records (EHRs) to automate results and prompt referrals, aiming to improve screening rates and facilitate early diagnosis and timely treatment. Objective: To increase DRS rates, facilitate early-stage DR detection, improve timely eye specialist follow-up, and assess the effect of DRS on patients' knowledge, attitudes, self-efficacy, and satisfaction. Design, Setting, and Participants: DRES-POCAI is a patient-level, multiclinic, open-label, parallel superiority randomized clinical trial at 2 FQHC sites of San Ysidro Health in San Diego County, California. The study recruitment targets 848 active FQHC patients aged 22 years or older with diabetes, no DRS in the prior 11 months, and scheduled medical visits during the intervention period. Patients with a history of retinopathy or retinal vascular occlusion and other physical or mental conditions are excluded. The study started in June 2024, with recruitment anticipated to conclude in August 2025 and follow-up until February 2026. Intervention: The intervention arm receives DRS at their primary care clinic using an AI-powered DRS system, with retinal image analysis to identify more than mild DR and vision-threatening DR. Results are immediately available in the EHRs, and practitioners receive risk-stratified referral recommendations. The usual care arm receives referrals to an FQHC optometrist or external eye care practitioner, with results transmitted to the medical home later. Main Outcomes and Measures: The primary outcome is DRS completion status. Secondary outcomes include DR diagnosis stage, specialist referrals, and participants' DR knowledge, attitudes, and intentions regarding future AI-powered DRS. Results: Findings will be disseminated in peer-reviewed publications after data collection and analysis. Conclusions and Relevance: DRES-POCAI will determine the effectiveness of an AI-powered DRS intervention to increase DRS rates in FQHC primary care workflows. Trial Registration: ClinicalTrials.gov Identifier: NCT06721351.

Indexed as

Artificial IntelligenceDiabetic RetinopathyMass ScreeningPoint-of-Care SystemsAdultElectronic Health RecordsEquivalence Trials as TopicFemaleHumansMaleMiddle AgedPrimary Health CareRandomized Controlled Trials as Topic

Identifiers

PMID41118165
PMCPMC12541539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.