Evidence map›Paper›PMID 41118076›Full record

ArticleJournal of ophthalmic inflammation and infection2025

Integrated imaging in rare eyelid lesions: a case report of palpebral dirofilariosis.

Luca Tinunin, Filippo Ugolini, Dario Giattini, Nicola Santoro

Abstract read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luca TinuninSection of Anatomic Pathology, Department of Health Sciences, University of Florence, Florence, Italy. luca.tinunin@unifi.it.ORCID http://orcid.org/0009-0005-2237-5406
Filippo UgoliniSection of Anatomic Pathology, Careggi University Hospital, Florence, Italy.
Dario GiattiniUnit of Ocular Oncology, Department of Surgery and Translational Medicine, Careggi University Hospital, Florence, Italy.
Nicola SantoroUnit of Ocular Oncology, Department of Surgery and Translational Medicine, Careggi University Hospital, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntegrated evaluation of clinical records, radiologic imaging, and histologic slides was key in the diagnosis of a rare ophthalmic infection such as Dirofilaria repens, an emerging zoonosis in many Mediterranean regions, where it is endemic in cats and dogs and can spread to humans through mosquitos of the genera Anopheles, Aedex and Culex. CASE REPORT: We present the case of a 64-year-old male with a subcutaneous nodule at the right medial canthus. Surgical excision was performed under the clinical suspicion of a sebaceous cyst, and the specimen was submitted for pathological examination. Histological analysis revealed a partially necrotic abscess with numerous eosinophils and multiple cross-sections of the body of a parasite. The integrated evaluation of CT, MRI and histologic sections were consistent with the diagnosis of infestation by a female Dirofilaria repens. DISCUSSION: In this report we discussed an illustrative case of Dirofilaria infestation, an uncommon condition, and illustrate the benefits of an integrated approach to the care of ophthalmic lesions. Indeed, direct access to digitalized images of different modalities is beneficial in reducing delays, increasing accuracy, and is beneficial for prompt medical care and accurate diagnosis. The rising incidence and the possibility of serious complications, especially for the less frequent localizations more typical of species other than Dirofilaria repens, translates the need for a more widespread knowledge of these zoonoses.

Indexed as

DirofilariosisIntegrated imagingOphthalmic pathologyPalpebral parasitosis

Identifiers

PMID41118076
PMCPMC12540220

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.