Evidence map›Paper›PMID 41118013›Full record

Trial reportLangenbeck's archives of surgery2025

Preoperative respiratory training with incentive spirometry for the prevention of pulmonary complications after liver surgery- a randomized pilot trial (PreSpi Trial).

Esther Giehl-Brown, Henriette Rangnick, Johannes Schweipert, Michael Halank, Dirk Koschel, Jürgen Weitz, Carina Riediger

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esther Giehl-Brown *Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Henriette Rangnick *Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Johannes SchweipertDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Michael HalankDivision of Pulmonology, Medical Department I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Dirk KoschelDivision of Pulmonology, Medical Department I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Jürgen WeitzDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Carina RiedigerDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany. carina.riediger@vinzenz.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative pulmonary complications (PPCs) following liver surgery are associated with considerable morbidity and mortality. Nevertheless, data regarding the effectiveness of short-term, self-conducted preoperative respiratory training on pulmonary function and its influence on postoperative recovery are limited.

methodsPatients scheduled for liver surgery at the University Hospital Dresden, were screened for eligibility and randomized 1:1 to the intervention or control group. The intervention consisted of self-conducted respiratory training with an incentive spirometer for 14 consecutive days before surgery. Pulmonary function was assessed using longitudinal bodyplethysmography. The feasibility of the study design and clinical outcomes were evaluated.

resultsSixty-two patients were screened, 50 participants (81%) were randomized. Twenty control and 21 intervention participants (66.1%) completed all assessments and were included in the final analysis. Participants in the intervention group were highly compliant with the proposed inhalation training. Preoperative risk stratification for PPCs conducted according to the ARISCAT score revealed a high risk for PPCs in > 90% of all patients. Pneumonia occurred in 0 of intervention patients compared to 5 (25%) in the control group (p = 0.016). Pleural effusion was observed in 8 (38.1%) of intervention patients versus 16 (80%) in the control group (p = 0.007).

conclusionThis pilot trial establishes the feasibility of a definitive randomized controlled trial to investigate the effect of short-term, self-conducted preoperative respiratory training on pulmonary function for the prevention of PPCs after hepatic resection.

Indexed as

Breathing ExercisesHepatectomyLung DiseasesPostoperative ComplicationsPreoperative CareSpirometryAgedFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsIncentive spirometryLiver surgeryPostoperative pulmonary complicationsPreoperative respiratory trainingRandomized pilot trial

Identifiers

PMID41118013
PMCPMC12540556

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.