Evidence map›Paper›PMID 41117950›Full record

ArticleArchives of microbiology2025

Lactobacillus acidophilus alleviates polysorbate-80-induced colitis through regulating intestinal microbiota and inhibiting indoleamine 2,3-dioxygenase 1.

Haibin Guan, Xinyuan Tian, Menghe Liu, Yanjun Yue, Jing He, Jianxia Gao, Song You

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haibin GuanSchool of Life Sciences and Biopharmaceutical Sciences, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe, Shenyang, 110016, People's Republic of China.
Xinyuan TianCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, People's Republic of China.
Menghe LiuCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, People's Republic of China.
Yanjun YueCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, People's Republic of China.
Jing HeCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, People's Republic of China.
Jianxia GaoCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, People's Republic of China.
Song YouSchool of Life Sciences and Biopharmaceutical Sciences, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe, Shenyang, 110016, People's Republic of China. 3585801344@qq.com.

Funding

2022 Inner Mongolia Autonomous Region Health Science and Technology Plan Project NO. 202201184the 2020 Natural Science Foundation Project of Inner Mongolia Autonomous Region NO. 2020MS08199
6 · The paper itself

Abstract

Polysorbate-80 is a prevalent food additive. However, prolonged administration of polysorbate-80 has been demonstrated to induce intestinal inflammation in animal models, there is no effective measure to deal with this hazard at present. In this study, colitis was induced using 1% of polysorbate-80 for 30 days, treated with (10

Indexed as

ColitisGastrointestinal MicrobiomeLactobacillus acidophilusPolysorbatesProbioticsAnimalsDisease Models, AnimalInterleukin-6MaleMiceTumor Necrosis Factor-alphaInterleukin-6PolysorbatesTumor Necrosis Factor-alphaIndoleamine 2,3-dioxygenase 1Intestinal microbiotaLactobacillus acidophilusPolysorbate-80-induced colitisQuinolinic acid

Identifiers

PMID41117950

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.