Evidence map›Paper›PMID 41117936›Full record

ArticlePediatric radiology2026

The gorilla lip sign: diagnostic utility of anteroposterior radiographs for pediatric talocalcaneal coalition.

Yueqiang Mo, Haodong Li, Peng Huang, Yanhui Jing, Bo Ning, Yuerong Zhang, Dahui Wang

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Article in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Yueqiang MoChildren's Hospital of Fudan University, Wanyuan Road 399, Minhang District, Shanghai, 201102, China.
Haodong LiChildren's Hospital of Fudan University, Wanyuan Road 399, Minhang District, Shanghai, 201102, China.
Peng HuangChildren's Hospital of Fudan University, Wanyuan Road 399, Minhang District, Shanghai, 201102, China.
Yanhui JingChildren's Hospital of Fudan University, Wanyuan Road 399, Minhang District, Shanghai, 201102, China.
Bo NingChildren's Hospital of Fudan University, Wanyuan Road 399, Minhang District, Shanghai, 201102, China.
Yuerong ZhangChildren's Hospital of Fudan University, Wanyuan Road 399, Minhang District, Shanghai, 201102, China. 410255400@qq.com.
Dahui WangChildren's Hospital of Fudan University, Wanyuan Road 399, Minhang District, Shanghai, 201102, China.

Funding

Fudan Fuxing Nursing Research Foundation FNF202346National Key Research and Development Program of China 2021YFC2701003
6 · The paper itself

Abstract

backgroundTalocalcaneal coalition is highly prevalent but diagnostically challenging due to the subtalar joint's complex anatomy, leading to frequent oversights on conventional radiographs. Existing signs rely primarily on lateral views, with variable sensitivity.

objectiveTo introduce and validate the "gorilla lip" sign on non-weight-bearing anteroposterior (AP) radiographs as a complementary diagnostic marker for talocalcaneal coalition. MATERIALS AND

methodsIn this retrospective study, non-weight-bearing AP ankle radiographs of 30 talocalcaneal coalition-confirmed feet (positive group) and 33 normal feet (negative group) from children aged ≤17 years were analyzed. The "gorilla lip" sign was defined by sustentaculum tali abnormalities: (1) osseous protuberance ≥50% medial malleolus height, (2) narrowed and rough articular surface, or (3) absent joint space. Three blinded observers independently assessed randomized images twice (2-month interval). Sensitivity, specificity, likelihood ratios, and inter-/intraobserver reliability were calculated.

resultsAcross two evaluations by three observers, sensitivity ranged from 77-93%, and specificity ranged from 85-100%. Positive likelihood ratios were ranging from 5.28 to infinite, indicating a high probability of talocalcaneal coalition when the sign is present, while low negative likelihood ratios (ranging from 0.07 to 0.24) suggest its absence is a strong indicator to rule out talocalcaneal coalition. The sign showed good interobserver reliability (Fleiss kappa, 0.65-0.70) and good to excellent intraobserver reliability (kappa, 0.67-0.87).

conclusionsThe "gorilla lip" sign is a highly sensitive, specific, and reproducible radiographic marker for diagnosing talocalcaneal coalition on non-weight-bearing AP ankle radiographs. Its application can complement traditional lateral view signs, enhancing diagnostic confidence and potentially reducing unnecessary examinations prompted by misdiagnosis.

Indexed as

CalcaneusRadiographySubtalar JointTarsal CoalitionAdolescentChildChild, PreschoolFemaleHumansInfantMaleReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityAdolescentObserver variationRadiographyReproducibility of resultsSensitivity and specificityTalocalcaneal coalition

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.