Evidence map›Paper›PMID 41117886›Full record

ArticleLa Radiologia medica2026

AI assistance improves radiology resident reader performance in CT diagnosis of intracranial hemorrhage.

Philipp Reschke, Leon D Gruenewald, Vitali Koch, Jennifer Gotta, Elena Höhne, Andreea-Ioana Nica, Ibrahim Yel, Tommaso D'Angelo, Giorgio Ascenti, Giuseppe M Bucolo and 5 more

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Article in La Radiologia medica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Philipp ReschkeInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Leon D GruenewaldInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Vitali KochInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Jennifer GottaInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Elena HöhneInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Andreea-Ioana NicaInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Ibrahim YelInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Tommaso D'AngeloDepartment of Biomedical Sciences and Morphological and Functional Imaging, University Hospital Messina, Messina, Italy. tommasodang@gmail.com.ORCID http://orcid.org/0000-0003-0004-6378
Giorgio AscentiDepartment of Biomedical Sciences and Morphological and Functional Imaging, University Hospital Messina, Messina, Italy.
Giuseppe M BucoloDepartment of Biomedical Sciences and Morphological and Functional Imaging, University Hospital Messina, Messina, Italy.
Ludovica R M LanzafameDepartment of Biomedical Sciences and Morphological and Functional Imaging, University Hospital Messina, Messina, Italy.
Erando JubicaInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Katrin EichlerInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Thomas J VoglInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.
Christian BoozInstitute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, University Hospital, Frankfurt Am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAccurate detection of intracranial hemorrhage (ICH) on non-contrast CT is critical in emergency settings, where missed diagnoses may delay treatment and worsen outcomes. While artificial intelligence (AI) models demonstrate high standalone performance, their additive value as a second reader for radiology residents is not well-established. MATERIAL AND

methodsThis retrospective study included 1,337 non-contrast head CT scans from 2015 to 2019 (670 ICH-positive and 667 ICH-negative). A previously validated AI model was used for ICH detection. Two radiology residents reviewed all scans in consensus, first without and later with AI support after a 30-day washout. Ground truth was established by expert consensus. Diagnostic performance metrics were calculated.

resultsAI assistance significantly improved radiology residents' diagnostic performance. Sensitivity increased from 0.85 to 0.94 and specificity from 0.87 to 0.97 (both p < 0.01), ROC-AUC rose from 0.86 to 0.95, and PR-AUC from 0.83 to 0.95 (p < 0.0001). The number of false negatives dropped from 101 to 41 with AI support. The greatest benefit was observed in subdural hematomas (SDH), where misses declined from 32 to 9 (20.3-5.7%; p < 0.001), corresponding to a 72% relative risk reduction. Misses also decreased for intraparenchymal hemorrhages (IPH: 37-20; RRR 46%) and subarachnoid hemorrhages (SAH: 30-11; RRR 63%). AI support reduced common error sources: small hemorrhage volume (48-21), atypical locations (30-12), and image-degrading artifacts (23-8). False positives fell from 87 to 21.

conclusionBy reducing diagnostic errors and supporting learning, AI serves as a valuable second reader for radiology residents-enhancing both patient safety and resident training in ICH detection.

Indexed as

Artificial IntelligenceClinical CompetenceInternship and ResidencyIntracranial HemorrhagesRadiologyTomography, X-Ray ComputedAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityAlgorithmsAutomated pattern recognitionComputed tomographyComputer ScienceLearning algorithmsMachine learning

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.