Evidence map›Paper›PMID 41117856›Full record

Trial reportJournal of anesthesia2026

Impact of the choice of general anesthesia agent on peri-operative oxygen supply-demand balance: a prospective quasi-randomized controlled trial comparing propofol and remimazolam.

Kenya Yarimizu, Masahiro Kuroki, Kiyotaka Soekawa, Tatsuya Hayasaka, Yu Onodera, Hiroto Suzuki, Hiroaki Toyama, Kaneyuki Kawamae

Abstract readRandomized Controlled TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in Journal of anesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Kenya YarimizuDepartment of Anesthesiology, Yamagata University Hospital, Yamagata, Japan. yarimizu.kenya@gmail.com.ORCID http://orcid.org/0000-0001-6857-8077
Masahiro KurokiDepartment of Anesthesiology, Yamagata University Hospital, Yamagata, Japan.
Kiyotaka SoekawaDepartment of Anesthesiology, Yamagata University Hospital, Yamagata, Japan.
Tatsuya HayasakaDepartment of Anesthesiology, Yamagata University Hospital, Yamagata, Japan.
Yu OnoderaDepartment of Anesthesiology, Yamagata University Hospital, Yamagata, Japan.
Hiroto SuzukiYamagata City Miyuki Hospital, Yamagata, Japan.
Hiroaki ToyamaDepartment of Anesthesiology, Yamagata University Hospital, Yamagata, Japan.
Kaneyuki KawamaeOhta-Nishinouti Hospital, Fukushima, Japan.

Funding

MEXT KAKENHI Grant No. 25K19863
6 · The paper itself

Abstract

purposeTo compare the effects of propofol and remimazolam on peri-operative oxygen supply-demand balance.

methodsThis prospective quasi-randomized controlled trial was carried out in a single tertiary care university hospital between January and October 2022, with patients (n = 50) aged 18-85 years undergoing major abdominal surgery. General anesthesia was induced and maintained with propofol or remimazolam. The primary endpoints were peri-operative oxygen consumption (VO

resultsAnesthesia induction significantly decreased VO

conclusionsAnesthesia induction suppressed metabolism. However, the choice of general anesthetic for scheduled major abdominal procedures did not significantly affect the oxygen supply-demand balance.

trial registrationUniversity Hospital Medical Information Network Clinical Trials Registry identifier: UMIN000046531.

Indexed as

Anesthesia, GeneralAnesthetics, GeneralAnesthetics, IntravenousOxygenOxygen ConsumptionPropofolAdolescentAdultAgedAged, 80 and overCarbon DioxideFemaleHumansMaleMiddle AgedProspective StudiesAnesthetics, GeneralAnesthetics, IntravenousCarbon DioxideOxygenPropofolIntravenous anestheticsOxygen metabolismPropofolRemimazolam

Identifiers

PMID41117856

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.