ArticleJournal of animal science2025
Effects of supplementation with Bifidobacterium animalis subsp. lactis CECT 8145-in live probiotic and heat-treated postbiotic form-on fecal metabolites, fecal microbiota, blood metabolites and systemic biomarkers of oxidative stress and inflammation, and white blood cell gene expression of adult cats.
Article in Journal of animal science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of Dietary Postbiotics Derived fromVeterinary sciences · 2026Article
- Postbiotic supplementation promotes gut barrier integrity and immune balance in cats via microbiota modulation.Frontiers in microbiology · 2025Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Probiotics and postbiotics have been linked with enhancement of gastrointestinal health. This study aimed to evaluate the longitudinal effects of daily supplementation of a pro- and a postbiotic on metabolic health, blood metabolites and systemic biomarkers of oxidative stress and inflammation, fecal fermentative end-products, the gastrointestinal microbiota and white blood cell gene expression of adult cats. The study was a double-blind parallel randomized design with 36 cats divided into 3 groups. Animals were fed a standard extruded commercial diet. The groups were control diet + placebo (maltodextrin carrier) (CON), control diet + probiotic (Bifidobacterium animalis subsp. lactis CECT 8145; daily dosage: 1010 CFU/day) (PRO), and control diet + postbiotic (Heat-treated Bifidobacterium animalis subsp. lactis CECT 8145) 1x1010 cells/day (POST). Longitudinal analyses were performed every 30 d for a total of 90 d. There was no observed effect on body weight (P > 0.05). At a species level, cats in the PRO group had an increased abundance of Bifidobacterium animalis over time (P < 0.05). Over time, CAZy genes between the PRO and POST groups presented similar output when compared to the CON group. There was no treatment by day effect of serum cytokines and chemokines (P > 0.05). Overall, the supplementation of the probiotic and postbiotic was safe and well tolerated during the supplementation period, showing similar physiological responses in this population of adult cats.
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Registered trials
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