Evidence map›Paper›PMID 41117507›Full record

ArticleApplied and environmental microbiology2025

Heterologous rhamnolipid biosynthesis by

Melanie Filbig, Philipp Otzen, Matti Froning, Hannah Braß, Alessandra Mauri, George Guo-Qiang Chen, Heiko Hayen, Till Tiso, Lars M Blank

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melanie FilbigiAMB - Institute of Applied Microbiology, ABBt - Aachen Biology and Biotechnology, RWTH Aachen University, Aachen, Germany.ORCID 0009-0009-3025-8807
Philipp OtzenInstitute of Inorganic and Analytical Chemistry, University of Münster, Münster, Germany.
Matti FroningInstitute of Inorganic and Analytical Chemistry, University of Münster, Münster, Germany.
Hannah BraßiAMB - Institute of Applied Microbiology, ABBt - Aachen Biology and Biotechnology, RWTH Aachen University, Aachen, Germany.
Alessandra MauriiAMB - Institute of Applied Microbiology, ABBt - Aachen Biology and Biotechnology, RWTH Aachen University, Aachen, Germany.
George Guo-Qiang ChenLab of Microbiology, School of Life Sciences, Tsinghua University, Beijing, China.
Heiko HayenInstitute of Inorganic and Analytical Chemistry, University of Münster, Münster, Germany.ORCID 0000-0002-4074-8545
Till TisoSystems Biotechnology, Technical Faculty, Bielefeld University, Bielefeld, Germany.
Lars M BlankiAMB - Institute of Applied Microbiology, ABBt - Aachen Biology and Biotechnology, RWTH Aachen University, Aachen, Germany.ORCID 0000-0003-0961-4976

Funding

Deutsche Forschungsgemeinschaft 390919832Horizon 2020 European Commission (EC) 870294
6 · The paper itself

Abstract

Rhamnolipids are glycolipids and, as such, biosurfactants with high surface activity, good biodegradability, low toxicity, and thus manifold applications. Although rhamnolipids have been extensively researched and are already produced industrially, the biosynthesis pathway has not yet been resolved beyond doubt. While the origin of the hydrophilic moiety is clear and all responsible genes and enzymes have been identified, the origin of the hydrophobic moiety, 3-(3-hydroxyalkanoyloxy) alkanoic acid, remains to be identified. Here, the involvement of the two central metabolic pathways, that is, fatty acid

Indexed as

Fatty AcidsGlycolipidsPseudomonas putidaBacterial ProteinsBiosynthetic PathwaysOxidation-ReductionPseudomonas aeruginosaBacterial ProteinsFatty AcidsGlycolipidsrhamnolipid13C-labelingbiosurfactantsFASIIGC-MSLC-MSmetabolic engineeringPseudomonas putidarhamnolipidβ-oxidation

Identifiers

PMID41117507
PMCPMC12628675

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.