ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025
Quantitative magnetic resonance angiography for early identification of in-stent stenosis post-flow diverter aneurysm embolization.
Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Not yet cited in PubMed.
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Abstract
BackgroundIn-stentstenosis (ISS) is a recognized complication following flow-diverting stent placement for intracranial aneurysms. Although typically asymptomatic and self-resolving, severe cases may result in ischemic complications. Gold-standard detection relies on invasive digital subtraction angiography (DSA). This study sought to determine whether quantitative magnetic resonance angiography with non-invasive optimal vessel analysis (qMRA NOVA) can accurately identify patients with ISS following flowdiverter placement.MethodsThis retrospective study evaluated 373 patients treated with flow-diverting stents at a single institution between 2017 and 2023. Sixteen patients met the inclusion criteria for DSA-confirmed ISS with matched post-procedure and follow-up NOVA imaging and catheter angiography. Vessel flow, velocity, and diameter were analyzed. Receiver operating characteristic (ROC) analysis was used to determine optimal thresholds for detecting ISS based on flow changes.ResultsAmong ISS patients, 88% demonstrated significant flow reductions in the treated vessel on follow-up NOVA (mean decrease: 76.2 ± 65.0 ml/min,
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