ArticleSmall methods2025
Continuous and Scalable Production of Uniform Au Nanocrystals Capped by Citrate Species in Flow Reactors for Lateral Flow Tests.
Article in Small methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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4 authors.
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Abstract
Gold (Au) nanocrystals with uniform sizes and shapes are critical for enhancing the sensitivity and reliability of lateral flow tests (LFTs). Herein, a modular platform based on flow reactors for continuous and scalable production of uniform Au nanocrystals, including clusters, small spheres, cubes, and large spheres is reported. It is demonstrated that the one-shot injection method commonly used with batch reactors can be readily adapted for continuous flow reactors, which also allow for on-line monitoring of growth kinetics using UV-vis spectroscopy. The uniform Au nanospheres exhibit narrower localized surface plasmon resonance peaks, greatly enhancing their mass-to-signal conversion ratio and diagnostic sensitivity relative to the Au nanoparticles currently used for commercial LFTs. Upon surface modification with citric acid in a flow reactor, the Au nanospheres show excellent colloidal stability, highlighting their promise for further functionalization and point-of-care diagnostics based on LFTs.
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