Observational studyClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Prevalence and Predictors of Non-adherence to Oral Anticoagulation Therapy Up To 24 Months After Acute Pulmonary Embolism: Results from a Prospective Observational Study.
Observational study in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BackgroundOral anticoagulation (OAC) therapy is essential to avoid venous thromboembolism recurrence, but drug-adherence sometimes might be poor.AimTo describe OAC adherence in patients after acute pulmonary embolism (PE) and to identify risk factors for non-adherence.MethodsWe prospectively evaluated 324 PE patients (mean age 62.9 ± 14.3, 51.5% male) after 3, 6, 12 and 24 months, resulting in 1620 study visits. Data were analyzed using multivariable logistic models.ResultsOut of the study population, 19 patients (5.9%) were identified to be non-adherent to OAC therapy. Significant predictors of non-adherence were a history of stroke and diabetes mellitus (DM) (OR = 6.07, 95% CI 1.58-23.36,
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