Trial reportAnaesthesia2026
Peri-operative rehabilitation in patients undergoing elective cardiac valve surgery: a randomised controlled trial.
Trial report in Anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Baseline peak VO₂ and treatment effect consistency of perioperative rehabilitation in cardiac valve surgery: an exploratory subgroup analysis of the PORT trial.BMC anesthesiology · 2026Trial
- Sex Differences in the Effects of Perioperative Rehabilitation on Postoperative Pulmonary Complications After Cardiac Valve Surgery: A Prespecified Subgroup Analysis of the PORT Randomized Trial.International journal of women's health · 2026Article
- Effects of liposomal bupivacaine versus ropivacaine for fascia iliaca compartment block on postoperative pain and delirium in elderly patients undergoing hip arthroplasty.American journal of translational research · 2026Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
introductionPatients with valvular heart disease are at high risk of postoperative pulmonary complications, which contribute to morbidity and mortality. However, few studies have focused specifically on peri-operative rehabilitation in this patient population. We aimed to evaluate whether peri-operative rehabilitation benefits patients undergoing elective cardiac valve surgery by reducing the incidence of postoperative pulmonary complications, the duration of postoperative hospitalisation and mortality.
methodsThis single-centre, randomised controlled trial compared usual care (usual care group) with a peri-operative rehabilitation bundle (rehabilitation group) comprising four components: education; inspiratory muscle training; active cycle of breathing techniques; and early mobilisation. The primary outcome was a composite measure of the occurrence of postoperative pulmonary complications within the first 7 days; incidence of prolonged postoperative hospitalisation > 7 days; and in-hospital all-cause mortality. Secondary outcomes included each component of primary outcome measure; duration of stay in the ICU; total duration of postoperative hospitalisation; and 3-month all-cause mortality.
resultsOn an intention-to-treat basis, data from 818 patients were analysed (419 allocated to the usual care group and 399 to the rehabilitation group). The primary composite outcome did not differ between groups, occurring in 224/419 (53.5%) patients allocated to the usual care group and 206/399 (51.6%) patients allocated to the rehabilitation group (odds ratio 0.88, 95%CI 0.66-1.17, p = 0.376). Postoperative pulmonary complications were present in 197 (47.1%) patients allocated to the usual care group and 161 (40.4%) patients allocated to the rehabilitation group (odds ratio 0.720, 95%CI 0.541-0.956, p = 0.023). There was no significant difference between the groups in terms of duration of postoperative hospital stay of > 7 days or in-hospital mortality. DISCUSSION: Peri-operative rehabilitation reduced the incidence of postoperative pulmonary complications in patients having surgery for valvular heart disease. We recommend incorporating comprehensive peri-operative rehabilitation into the clinical management of these patients.
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