Evidence map›Paper›PMID 41116928›Full record

ArticleCureus2025

Intravitreal Faricimab for the Management of Bilateral Macular Neovascularization Secondary to Macular Telangiectasia Type 2.

Prasan Rao, Anupama Rao, Jabeen Mohammed Jaffer, Ansu Sara John

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Prasan RaoOphthalmology, Medcare Eye Centre, Dubai, ARE.
Anupama RaoOphthalmology, Medcare Eye Centre, Dubai, ARE.
Jabeen Mohammed JafferOphthalmology, Medcare Eye Centre, Dubai, ARE.
Ansu Sara JohnOphthalmology, Medcare Eye Centre, Dubai, ARE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macular telangiectasia type 2 (MacTel2) is a bilateral neurodegenerative disease characterized by telangiectasia of macular vasculature and foveal atrophy that is typically acquired during middle age. It may lead to visual loss due to progressive reduction of photoreceptor function or secondary to macular neovascularization. We report a case of bilateral macular neovascularization associated with MacTel2, which was treated with intravitreal faricimab injections. A 52-year-old female presented with a history of progressive reduction of vision in both eyes. Dilated fundus examination revealed the presence of perifoveal telangiectasia and right-angled venules in the juxtafoveal region. Diagnosis of MacTel2 and associated macular neovascularization (MNV) was confirmed with fundus fluorescein angiography (FA), optical coherence tomography (OCT), and angiography (OCTA). The patient was treated with three bilateral injections of faricimab on a monthly basis. Following the last injection, there was improvement of best corrected visual acuity (BCVA), reduction of macular thickening on OCT, and shrinkage of the MNV on OCTA. This is the first reported case of usage of intravitreal injection of faricimab for the management of visual loss due to macular neovascularization due to MacTel2.

Indexed as

ellipsoid zone integrityfaricimabintraretinal cavitationmacular neovascularizationmacular telangiectasia type 2

Identifiers

PMID41116928
PMCPMC12535685

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.