Evidence map›Paper›PMID 41116907›Full record

ArticleCase reports in pediatrics2025

Bifocal

Corina Ramona Nicolescu, Sandrine Thouvenin Doulet, Lucie Bazus, Jean-Louis Stephan

Abstract readCase Reports
In one paragraph

Article in Case reports in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Corina Ramona NicolescuDepartment of Pediatric Endocrinology and Diabetes, University Hospital Saint-Etienne, Avenue Albert Raimond, Saint-Priest en Jarez 42270, France.ORCID https://orcid.org/0000-0001-7197-3078
Sandrine Thouvenin DouletDepartment of Pediatric Hematology and Oncology, University Hospital Saint-Etienne, Avenue Albert Raimond, Saint-Priest en Jarez 42270, France.
Lucie BazusDepartment of Pediatric Endocrinology and Diabetes, University Hospital Saint-Etienne, Avenue Albert Raimond, Saint-Priest en Jarez 42270, France.
Jean-Louis StephanDepartment of Pediatric Hematology and Oncology, University Hospital Saint-Etienne, Avenue Albert Raimond, Saint-Priest en Jarez 42270, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intracranial germ cell tumors (GCTs) are rare in the pediatric population. They are classified as germinoma and nongerminomatous and may secrete specific proteins such as Case: A 13-year-old boy presented with a first generalized tonic-clonic seizure after six months of headaches, vomiting, polyuria, and polydipsia. Examination showed pubertal penile length with peripubertal testes. Laboratory assessment revealed panhypopituitarism with suppressed gonadotropins and elevated testosterone. Brain magnetic resonance imaging (MRI) demonstrated bifocal lesions (pineal and suprasellar) with obstructive hydrocephalus. Cerebrospinal fluid (CSF) sample obtained via temporary external ventricular drain (EVD) showed a normal cytology, confirming a Conclusion: Discordant clinical and biochemical puberty (penile enlargement with small testes and high testosterone with suppressed gonadotropins) should prompt

Indexed as

gonadotrophin-independent pubertyhuman chorionic gonadotropinintracranial germinomaparaneoplastic syndrome

Identifiers

PMID41116907
PMCPMC12535809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.