Evidence map›Paper›PMID 41116870›Full record

ArticleInternational journal of nanomedicine2025

Oral Toxicity Study of Silicon Dioxide Nanoparticles on Fertility and Early Embryonic Development in Mice.

Ji-Seong Jeong, Sang Yun Kim, Sun-Young Lee, Jeong-Dong Park, In-Su Wi, Cheoljin Park, Jeong Hwan Kim, Donghee Kim, Wonjun Jeong, Min-Sung Kang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ji-Seong JeongDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Sang Yun KimDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Sun-Young LeeDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Jeong-Dong ParkDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
In-Su WiDevelopmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
Cheoljin ParkLaboratory Animal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
Jeong Hwan KimLaboratory Animal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
Donghee KimLaboratory Animal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
Wonjun JeongLaboratory Animal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.
Min-Sung KangJeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.
Se-Woong ParkJeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.
Sung-Hwan KimJeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.
Jinsoo LeeLaboratory Animal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea.ORCID 0000-0002-8700-5079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Silicon dioxide nanoparticles (SiO Methods: In this study, we investigated the potential reproductive and developmental toxicity of SiO Results: Oral administration of SiO Conclusion: The results demonstrated that oral exposure to SiO

Indexed as

Embryonic DevelopmentFertilityNanoparticlesSilicon DioxideAdministration, OralAnimalsFemaleMaleMicePregnancySilicon Dioxidedevelopmental toxicologyE 551hazard identificationnanotoxicologyreproductive toxicology

Identifiers

PMID41116870
PMCPMC12535729

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.