ReviewNature and science of sleep2025
The Mechanisms of Magnesium in Sleep Disorders.
Review in Nature and science of sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Effects of almond consumption on sleep quality in adults: a randomized controlled trial.Frontiers in nutrition · 2026Trial
- Targeting the Sleep-Glymphatic-Vascular Continuum in Cerebral Small Vessel Disease: A Nutritional Perspective on Neuroprotective Potential of Tocotrienols (T3).Life (Basel, Switzerland) · 2026Review
- Magnesium and Zinc Are Associated with Sleep Quality in Saudi Adults: Evidence from a Cross-Sectional Study.Nutrients · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep is a highly elaborate biological occurrence, necessitating the combined action and participation of diverse brain regions. The sleep-wake cycle is regulated by a multitude of factors, including various hormones produced by the hypothalamus and external stimuli. Sleep disorders can accelerate the progression of numerous diseases or directly trigger the onset of many health conditions. However, the specific regulatory mechanisms remain elusive. In recent years, the role of magnesium in sleep disorders has garnered considerable attention. Magnesium not only reduces the excitability of the nervous system and alters muscle relaxation but also regulates cellular biological clocks, energy balance, and circadian rhythms, playing a crucial role in sleep regulation. Magnesium deficiency not only shortens the effective sleep duration but also impairs sleep quality, leading to various specific sleep disorders. Additionally, magnesium supplements can improve sleep parameters in a variety of sleep-related diseases, especially those associated with the occurrence and development of sleep disorders. Therefore, a more in-depth understanding of the impact of magnesium on sleep disorders may reveal new therapeutic targets for sleep-related diseases. In this review, we comprehensively summarize the latest key findings on the mechanism of action of magnesium in sleep health and its role in initiating or exacerbating common sleep disorders, providing new insights into the diagnosis and treatment of sleep disorder-related diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.