ArticleBrain and behavior2025
Changes of Basilar Artery in Patients With Migraine: A Case-Control Study Based on 3T MRI.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Changes of Basilar Artery in Patients With Migraine: A Case-Control Study Based on 3T MRI.Brain and behavior · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
Abstract
objectiveAs a neurovascular disorder, migraine currently lacks well-established macroscopic biomarkers detectable by magnetic resonance angiography (MRA). While the basilar artery (BA) has been implicated in migraine pathophysiology, this relationship remains poorly characterized. This study investigates whether BA morphological parameters could serve as diagnostic biomarkers for migraine and predictive markers for disease progression.
methodsThis study included 41 healthy controls (HCs), 41 episodic migraine (EM) patients, and 95 chronic migraine (CM) patients who completed both MRI examinations and standardized questionnaires. Using established diagnostic criteria for vertebrobasilar dolichoectasia (VBD), we quantified the diameter, length, and height of the BA bifurcation. Furthermore, we measured the superior cerebellar artery (SUCA) outlet angle and basilar artery lateral displacement (BALD). These BA-derived metrics were subsequently incorporated into multivariable logistic regression models to assess their predictive value for migraine chronification.
resultsNo significant differences were found in BA diameter, BA length, BADE, or VBD when comparing either EM or CM groups with HCs. However, both BALD and SUCA outlet angles showed significant intergroup differences. There was a statistically significant difference in BADE between EM and CM. In the logistic regression, migraine was significantly associated with both BALD and SUCA outlet angles. In the multinomial logistic regression analysis, EM was significantly associated with SUCA outlet angle, while CM was significantly associated with both BALD and SUCA outlet angle.
conclusionsOur data suggest that the reduced SUCA outlet angle may represent a risk factor for migraine and could potentially serve as an imaging biomarker. Additionally, BALD may constitute an independent risk factor for CM and could function as an MRA biomarker for migraine chronicity. Potential indicators related to the basilar artery may influence migraine attacks by affecting hemodynamic changes in migraine pathophysiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.