ArticleBrain and behavior2025
Association Between Interictal Sensory Hypersensitivities and Vestibular Symptoms in Migraine: A Cross-Sectional Study.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Hypothalamic subregional volume in relation to VSS-C total symptom burden in women with migraine: an exploratory cross-sectional MRI study.Frontiers in neurology · 2026Article
- Association Between Interictal Sensory Hypersensitivities and Vestibular Symptoms in Migraine: A Cross-Sectional Study.Brain and behavior · 2025Article
- The interictal symptom burden in vestibular migraine-a condition in need of recognition.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDizziness and vertigo are common in migraine patients. This study investigated the relationship between vestibular symptoms and interictal hypersensitivities.
methodsA cross-sectional survey was conducted in migraine patients from a headache unit and a neurology clinic.
resultsAmong 274 participants (87.2% female, mean age 41.7 ± 12.4 years), interictal sensory hypersensitivities were common: 76 (27.7%) reported photophobia, 67 (24.5%) phonophobia, and 69 (25.2%) osmophobia. Vestibular symptoms were also common: dizziness 148 (54.0%) and vertigo 119 (43.8%).Vestibular symptoms were more prevalent in patients with interictal symptoms: photophobia (dizziness 77.6% vs. 47.1%, p < 0.001; vertigo 68.0% vs. 33.8%, p < 0.001), phonophobia (dizziness 74.6% vs. 47.3%, p < 0.001; vertigo 61.2% vs. 37.7%, p < 0.001), and osmophobia (dizziness 66.7% vs. 49.8%, p = 0.015; vertigo 56.5% vs. 39.4%, p = 0.011). Patients with interictal sensory hypersensitivities had higher Dizziness Handicap Inventory (DHI) scores: photophobia (57.9 ± 20.7 vs. 45.1 ± 22.3, p < 0.001), phonophobia (55.6 ± 20.2 vs. 47.5 ± 23.2, p = 0.037), and osmophobia (53.1 ± 22.3 vs. 48.9 ± 22.5, p = 0.299).In multivariable analysis, the number of interictal hypersensitivities predicted dizziness (OR 1.74, p = 0.002) and vertigo (OR 1.72, p < 0.001). Having ≥ 15 headache days/month was the strongest predictor of dizziness (OR 3.30, p = 0.001), while nausea was the strongest predictor of vertigo (OR 3.86, p < 0.001).
conclusionsVestibular symptoms are highly prevalent in migraine and strongly associated with interictal hypersensitivities. The number of affected sensory modalities predicts both prevalence and severity. Higher burdens of migraine and nausea are key predictors of dizziness and vertigo, respectively.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.