Evidence map›Paper›PMID 41116308›Full record

ArticleJournal of clinical apheresis2025

Therapeutic Plasma Exchange Shows Greater Efficacy Than DFPP in Reducing FT3 and FT4 Levels in Thyrotoxicosis due to Amiodarone-Induced Thyrotoxicosis Type 2.

Marion Gerbal, Olivier Gilly, Marie-Alix Joyeux, Olivier Moranne

Abstract readCase Reports
In one paragraph

Article in Journal of clinical apheresis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marion GerbalService Néphrologie-Dialyse-Aphérèse, Hôpital Universitaire de Nîmes, Nîmes, France.
Olivier GillyService Endocrinologie, Hôpital Universitaire de Nîmes, Nîmes, France.
Marie-Alix JoyeuxService Endocrinologie, Hôpital Universitaire de Nîmes, Nîmes, France.
Olivier MoranneService Néphrologie-Dialyse-Aphérèse, Hôpital Universitaire de Nîmes, Nîmes, France.ORCID https://orcid.org/0000-0002-3127-1415

Funding

Hopital univesitaire de Nimes
6 · The paper itself

Abstract

The American Society for Apheresis (ASFA) recommendations only mention using therapeutic plasma exchange (TPE) to treat drug-resistant thyroid storms. Double filtration plasmapheresis (DFPP) is a therapeutic apheresis procedure with the advantage of being semi-selective, making it possible to limit albumin losses and reduce the volume of replacement fluid. However, there have been no studies comparing the efficacy and tolerability of TPE and DFPP for this specific indication. We hereby report the observation of 2 patients treated for thyroid storms due to amiodarone-induced thyrotoxicosis who were each able to benefit from TPE as well as DFPP sessions, enabling us to compare the purification of free thyroid hormones and tolerance of these two treatments. TPE showed greater efficiency in removing thyroid hormones with the same tolerability as DFPP.

Indexed as

AmiodaronePlasma ExchangePlasmapheresisThyrotoxicosisThyroxineTriiodothyronineAnti-Arrhythmia AgentsHumansTreatment OutcomeAmiodaroneAnti-Arrhythmia AgentsThyroxineTriiodothyroninedouble filtration plasmapheresistherapeutic plasma exchangethyroid storm

Identifiers

PMID41116308
PMCPMC12538030

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.