Evidence map›Paper›PMID 41116158›Full record

Observational studyBMC infectious diseases2025

Impact of non-pharmaceutical interventions of the COVID-19 pandemic on the trend of seasonal influenza in Kingdom of Saudi Arabia.

Abdulilah Alqarny, Maged El-Setouhy, Majed A Alotayfi, Mahmoud M Ali

Abstract readObservational Study
In one paragraph

Observational study in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdulilah AlqarnyMinistry of Health, Jazan, Kingdom of Saudi Arabia.
Maged El-SetouhyDepartment of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.
Majed A AlotayfiMinistry of Health, Jazan, Kingdom of Saudi Arabia.
Mahmoud M AliFaculty of Pharmacy, Assiut Branch, Al-Azhar University, Assiut, 71524, Egypt. MahmoudEbrahim.4.2045@azhar.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe implementation of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic has significantly affected the transmission dynamics of respiratory viruses globally. This study aimed to evaluate the impact of COVID-19 related NPIs on the trends of seasonal influenza in the Jazan region of southern Saudi Arabia.

methodsA retrospective observational study was conducted from January 2017 to December 2023. Data on laboratory-confirmed cases of seasonal influenza and COVID-19 were obtained from the Saudi Ministry of Health databases. The analysis compared influenza activity before and during the COVID-19 pandemic, focusing on incidence fluctuations, demographic characteristics, and the timing relative to the implementation and relaxation of NPIs.

resultsInfluenza cases declined from 449 in 2020 to 46 in 2021 (p < 0.001) during periods of strict NPI enforcement before rebounding to 430 in 2022 and 1,001 in 2023 (p < 0.001). COVID-19 cases peaked between 2020 and 2022 and showed a significant inverse correlation to influenza activity (p < 0.001). Influenza predominantly affected Saudis (88.7%) versus non-Saudis (11.3%) (p < 0.001), while COVID-19 cases were mainly among Saudis (84.3%) (p < 0.001). Age and gender distributions showed significant shifts post-NPI relaxation (p < 0.01), with influenza affecting 5-14-year-olds and 25-64-year-olds more prominently, and a gender shift from male to balanced or female predominance in recent years (p < 0.05).

conclusionCOVID-19 NPIs substantially reduced seasonal influenza transmission in the Jazan region. These findings highlight the collateral benefits of public health measures during pandemics and suggest that continued surveillance and targeted NPIs can be valuable in controlling seasonal influenza. Future strategies should integrate influenza vaccination campaigns with pandemic preparedness plans, considering regional specificities.

Indexed as

COVID-19Influenza, HumanAdolescentAdultAgedChildChild, PreschoolFemaleHumansIncidenceInfantMaleMiddle AgedPandemicsRetrospective StudiesSARS-CoV-2COVID-19Influenza surveillanceNon-pharmaceutical interventions (NPIs)Seasonal influenza trends

Identifiers

PMID41116158
PMCPMC12538797

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.