Evidence map›Paper›PMID 41116091›Full record

ArticleObesity surgery2025

Chronic Abdominal Pain After Roux-en-Y Gastric Bypass Surgery: A Prospective Cohort Study with 2-Year Follow-Up in a Swedish Population.

Angelos Al Nimer, Hanna de la Croix, Monika Fagevik Olsén, Anna Elmered, Eva Haglind, Lars Fändriks, Eva Angenete, Hans Axelsson, Srdjan Kostic, Ville Wallenius

Abstract read
In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Angelos Al NimerGastroIntestinal Metabolism Science lab (GIMS), Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. angelos.al.nimer@gu.se.
Hanna de la CroixDepartment of Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Monika Fagevik OlsénDepartment of Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Anna ElmeredDepartment of Surgery, Skaraborgs Hospital, Skövde, Sweden.
Eva HaglindDepartment of Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Lars FändriksGastroIntestinal Metabolism Science lab (GIMS), Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Eva AngeneteDepartment of Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Hans AxelssonGastroIntestinal Metabolism Science lab (GIMS), Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Srdjan KosticGastroIntestinal Metabolism Science lab (GIMS), Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ville WalleniusGastroIntestinal Metabolism Science lab (GIMS), Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Funding

Gothenburg Medical Association 1019715Stiftelsen Erik and Lily Philipsons Minnesfond MRC_MC_UU_12012/5Swedish Research Council 2023-02357Västra Götalandsregionen ALFGBG-1006591
6 · The paper itself

Abstract

backgroundThe risk of developing chronic abdominal pain after Roux-en-Y gastric bypass (RYGB) surgery has come under scrutiny. Few prospective studies exist on this subject. The aim of this prospective paired analysis cohort study was to evaluate the risk of developing chronic abdominal pain and QoL 2 years after RYGB surgery.

methodsAn unselected cohort of 107 patients living with obesity, scheduled to undergo elective RYGB surgery, filled out the study questionnaires before surgery. Two years after surgery, 84 patients responded to the questionnaires, resulting in a response rate of 78.5%.

resultsThe gastrointestinal symptom rating scale showed no change for diarrhea, indigestion, or obstipation, but on the other hand, a tendency to increased abdominal pain (p = 0.05) 2 years after RYGB. Gastroesophageal reflux symptoms decreased (2.1 ± 1.3 to 1.4 ± 0.9; p < 0.0001). Pain anxiety using the Pain Catastrophizing Scale decreased (from 13.5 ± 11.3 preoperatively to 10.1 ± 9.4 postoperatively, p = 0.001). The Hospital Anxiety and Depression Scale showed a decreased score for depression (4.4 ± 3.7 to 2.4 ± 3.3, p < 0.0001), but no change for anxiety. Quality of life increased significantly (EQ5D-3L health state from 0.69 ± 0.25 to 0.83 ± 0.23, p < 0.0001; EQ VAS: from 57.4 ± 19.6 to 80.1 ± 16.3, p < 0.001). Self-reported physical activity, according to the Saltin-Grimby Physical Activity Level Scale (SGPALS), increased (preoperative: median = 2, Q1 = 1, Q3 = 2; postoperative: median = 2, Q1 = 2, Q3 = 2.75, p < 0.0001).

conclusionsOur study indicates no significant increase in abdominal pain but decreased pain anxiety 2 years after RYGB surgery. Self-reported physical activity, depression symptoms, and general quality-of-life were improved compared to baseline values.

Indexed as

Abdominal PainChronic PainGastric BypassObesity, MorbidAdultAnxietyDepressionFemaleFollow-Up StudiesGastroesophageal RefluxHumansMaleMiddle AgedPain MeasurementPostoperative PainProspective StudiesAnxietyChronic abdominal painDepressionGastrointestinal symptomsObesityPhysical activityPreoperativeQuality of lifeRoux-en-Y gastric bypass

Identifiers

PMID41116091
PMCPMC12722377

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.