Evidence map›Paper›PMID 41116036›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

The association of NICU capacity strain with neonatal mortality and morbidity.

Elizabeth G Salazar, Molly Passarella, Brielle Formanowski, Jeannette Rogowski, Erika M Edwards, Scott D Halpern, Ciaran Phibbs, Scott A Lorch

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Elizabeth G SalazarDivision of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. salazare@email.chop.edu.ORCID http://orcid.org/0000-0001-6998-5977
Molly PassarellaDivision of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Brielle FormanowskiDivision of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Jeannette RogowskiThe Pennsylvania State University, University Park, PA, USA.ORCID http://orcid.org/0000-0002-1078-8749
Erika M EdwardsVermont Oxford Network, Burlington, VT, USA.
Scott D HalpernPerelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Ciaran PhibbsStanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-4353-3507
Scott A LorchDivision of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Funding

Hospital Financial Health, NICU Strain, and Neonatal Outcome Variation and Subpopulation DisparitiesK23HD115872 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI Elizabeth G Salazar · 2025 to 2026
$319k
NICHD NIH HHS K23 HD115872U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) K23HD115872
6 · The paper itself

Abstract

objectiveTo examine the association of admission NICU capacity strain with neonatal mortality and morbidity. STUDY

design2008-2021 South Carolina cohort using linked vital statistics and discharge data of 22-44 weeks GA infants, born at hospitals with ≥ level 2 unit and ≥5 births <34 weeks GA/year. The exposure was deciles of admission capacity strain, defined as the sum of infants ≤44 weeks GA with a congenital anomaly plus infants <34 weeks GA. The primary outcome was a composite of mortality and term and preterm complications. We used Poisson generalized linear mixed models to examine the association of exposure with outcome adjusting for patient and hospital characteristics.

resultsWe studied 64,647 infants from 30 hospitals. High capacity strain was associated with increased risk of mortality and morbidity adjusting for patient/hospital factors (for example, tenth decile aIRR 1.14, 95% CI 1.03-1.27).

conclusionCapacity strain is associated with adverse NICU outcomes.

Indexed as

Infant MortalityInfant, Premature, DiseasesIntensive Care Units, NeonatalFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematureLinear ModelsMaleSouth Carolina

Identifiers

PMID41116036
PMCPMC12717003

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.