Evidence map›Paper›PMID 41115889›Full record

SynthesisTranslational psychiatry2025

A systematic review with meta-analysis on the relation between acute stress, alcohol consumption and cortisol levels in individuals with a personal, familial or no alcohol use disorder.

Lisa J Weckesser, Maximilian Pilhatsch, Markus Muehlhan, Tanja Endraß, Robert Miller

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lisa J WeckesserInstitute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany. lisa.weckesser@tu-dresden.de.
Maximilian PilhatschDepartment of Psychiatry and Psychotherapy, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
Markus MuehlhanDepartment of Psychology / ICAN Institute of Cognitive and Affective Neuroscience, MSH Medical School Hamburg, Hamburg, Germany.ORCID http://orcid.org/0000-0002-8855-8724
Tanja EndraßInstitute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-8845-8803
Robert MillerInstitute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany. r.miller@phb.de.ORCID http://orcid.org/0000-0002-8665-5248

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) MI-2075/4-1Deutsche Forschungsgemeinschaft (German Research Foundation) WE- 6465/2-1
6 · The paper itself

Abstract

The self-medication hypothesis posits that alcohol is consumed to cope with stress, but corresponding evidence (incl. its impact on physiological stress markers) is heterogeneous. Thus, this systematic review examined the relationship between acute stress, acute alcohol consumption, and cortisol levels in individuals with varying alcohol use disorder (AUD) statuses. Following PRISMA guidelines, records from PubMed/Medline, Web of Science, and PsycInfo up to 16/05/2025 were analysed. We included 53 experimental and 31 observational studies that reported alcohol consumption volume after stress versus control conditions or measured cortisol recovery (C

Indexed as

Alcohol DrinkingAlcoholismHydrocortisoneStress, PsychologicalHumansHydrocortisone

Identifiers

PMID41115889
PMCPMC12537857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.