Evidence map›Paper›PMID 41115756›Full record

ArticleJournal of the American Board of Family Medicine : JABFM2025

Gastrointestinal Conditions and New Diagnosis of Alcohol Use Disorder.

Kimberly Schiel, Timothy Chrusciel, Richard Gruzca, Jeffrey F Scherrer

Abstract read
In one paragraph

Article in Journal of the American Board of Family Medicine : JABFM, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kimberly SchielFrom the Department of Family and Community Medicine, Saint Louis University School of Medicine (KS, RG, JFS); Advanced HEAlth Data (AHEAD) Research Institute, Saint Louis University School of Medicine (TC, RG, JFS); Department of Health and Clinical Outcomes Research, Saint Louis University School of Medicine. Salus Center (TC, RG); Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine (JFS). Kimberly.schiel@ssmhealth.com.
Timothy ChruscielFrom the Department of Family and Community Medicine, Saint Louis University School of Medicine (KS, RG, JFS); Advanced HEAlth Data (AHEAD) Research Institute, Saint Louis University School of Medicine (TC, RG, JFS); Department of Health and Clinical Outcomes Research, Saint Louis University School of Medicine. Salus Center (TC, RG); Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine (JFS).
Richard GruzcaFrom the Department of Family and Community Medicine, Saint Louis University School of Medicine (KS, RG, JFS); Advanced HEAlth Data (AHEAD) Research Institute, Saint Louis University School of Medicine (TC, RG, JFS); Department of Health and Clinical Outcomes Research, Saint Louis University School of Medicine. Salus Center (TC, RG); Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine (JFS).
Jeffrey F ScherrerFrom the Department of Family and Community Medicine, Saint Louis University School of Medicine (KS, RG, JFS); Advanced HEAlth Data (AHEAD) Research Institute, Saint Louis University School of Medicine (TC, RG, JFS); Department of Health and Clinical Outcomes Research, Saint Louis University School of Medicine. Salus Center (TC, RG); Department of Psychiatry and Behavioral Neuroscience, Saint Louis University School of Medicine (JFS).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the availability of safe and effective outpatient treatments for alcohol use disorder (AUD), primary care physicians screen and treat only a fraction of their patients with AUD. To better detect AUD, it may be effective to evaluate whether the known gastrointestinal consequences of heavy alcohol consumption are linked to subsequent AUD diagnoses. This study examined whether irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD) and gastritis/ulcer were associated with a new AUD diagnosis.

methodsDeidentified medical record data from a large Midwestern health care system was used to identify primary care patients without an AUD diagnosis in 2020 and 2021. Separate multivariate regression models were computed to estimate the association between each GI condition measured in 2020 and 2021 and odds of AUD diagnoses in follow-up (2022 to 2023).

resultsThe average age was 56.0 (SD 17.1) years old. Patients were most commonly White race (87.6%). Gastroesophageal reflux disease (GERD) (24.8%) was much more prevalent than either IBS (3.4%) or gastritis/ulcer (2.5%). After adjusting for covariates, there was no significant association between gastritis/ulcer or IBS and a new diagnosis of AUD within 2 years. However, after adjusting for all covariates GERD was significantly associated with new AUD diagnoses (OR = 1.18; 95% CI: 1.10-1.26).

conclusionsThis study suggests that primary care physicians should screen their GERD patients for AUD, as these patients are at higher risk of being diagnosed with AUD within 2 years. Further research is needed to determine patient acceptability to discussing AUD following a GERD diagnosis as compared with standard screening.

Indexed as

AlcoholismGastrointestinal DiseasesAdultAgedFemaleGastritisGastroesophageal RefluxHumansIrritable Bowel SyndromeMaleMiddle AgedPrevalencePrimary Health CareAlcohol DrinkingAlcohol Use DisorderGastritisGastroesophageal Reflux DiseaseIrritable Bowel SyndromeMental HealthPrimary Health Care

Identifiers

PMID41115756
PMCPMC12978582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.