Evidence map›Paper›PMID 41115161›Full record

ReviewCirculation2025

A Crossroads in Cardiovascular Medicine: Progress and Barriers to Impact.

Jessica A Regan, Melissa H Laitner, Victor J Dzau

Abstract readReview
In one paragraph

Review in Circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jessica A ReganDivision of Cardiology (J.A.R., V.J.D.), Duke University School of Medicine, Durham, NC.ORCID 0000-0002-3541-8146
Melissa H LaitnerNational Academy of Medicine, Washington, DC (M.H.L., V.J.D.).ORCID 0000-0002-5256-5965
Victor J DzauDivision of Cardiology (J.A.R., V.J.D.), Duke University School of Medicine, Durham, NC.ORCID 0000-0002-8280-519X

Funding

Novel approaches for cardiac reprogramming: Exosome delivery of reprogramming miRNAs and repressor targeting siRNAsR01HL178582 · NHLBI · DUKE UNIVERSITY · PI Conrad Hodgkinson · 2025 to 2026
$983k
Age-Related Clonal Hematopoiesis of Indeterminate Potential (CHIP) in Exercise ResponsivenessK38HL175026 · NHLBI · DUKE UNIVERSITY · PI REGAN, JESSICA ANN · 2024 to 2025
$210k
NHLBI NIH HHS K38 HL175026NHLBI NIH HHS R01 HL178582
6 · The paper itself

Abstract

During the past 75 years, advances in cardiovascular science and technology have significantly reduced morbidity and mortality. In 2012, Drs Nabel and Braunwald reviewed this progress in

Indexed as

CardiologyCardiovascular DiseasesHumansartificial intelligencecardiovascular mortalitydigital healthinnovationprevention

Identifiers

PMID41115161
PMCPMC12687667

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.