SynthesisPsychological trauma : theory, research, practice and policy2026
Treatment for co-occurring posttraumatic stress disorder and substance use disorders among veterans and civilians: A test of causally moderated comparative effectiveness.
Synthesis in Psychological trauma : theory, research, practice and policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
objectiveThe prevalence and negative sequelae of co-occurring posttraumatic stress disorder and substance use disorder (PTSD + SUD) are well documented. Findings from evidence syntheses regarding which PTSD + SUD treatments work best overall have been mixed, potentially because these treatments are not equally effective for all PTSD + SUD patient subgroups. Epidemiological and qualitative research suggest that veteran status may be related to differential PTSD + SUD treatment response. This study, applying recent quantitative methodological advances in evidence synthesis, is the first to examine the potential moderating effect of veteran status on PTSD + SUD treatment outcome.
methodWe report secondary analyses of psychotherapy arm data (
resultsTests of causally moderated comparative effectiveness showed that trauma-focused psychotherapy targeting PTSD and integrated trauma-focused psychotherapy targeting PTSD and SUD were both superior to treatment as usual for alcohol use severity outcomes, and this effect was stronger for veterans than civilians. Analyses did not provide evidence for differential response to active PTSD + SUD psychotherapies, relative to treatment as usual, on PTSD or drug use severity outcomes as a function of veteran status.
conclusionsFindings lend support for delivering trauma-focused psychotherapies to patients with PTSD + SUD, especially veterans, and point to important future directions for inquiries into optimizing patient matching to PTSD + SUD treatment. (PsycInfo Database Record (c) 2026 APA, all rights reserved).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.